Research Article
The Cooccurrence of Obesity, Osteoporosis, and Sarcopenia in the Ovariectomized Rat: A Study for Modeling Osteosarcopenic Obesity in Rodents
Table 3
The effects of ovariectomy (ovx) and 17β-estradiol (ovx + E2) on bone mineral density and bone mineral content of the 4th lumbar and right tibia in rats with initial ages of five and ten months. The mean tibial and vertebral bone mineral density and bone mineral content of ovx rats were significantly lower in comparison with sham rats in both age groups and E2 administration prevented the bone loss.
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Values are means ± SEM. Values that do not share the same superscript letters in each age category are significantly () different from each other. BMD, bone mineral density; BMC, bone mineral content ( per treatment group). |