Age- and Gender-Related Differences in Renal Vascular Responses to Angiotensin II in Rats: The Role of the Mas Receptor
Table 1
The values of body weight (BW), kidney weight (KW), and KW/100 g BW in all experimental groups.
Age
Gender
Group
BW (g)
Left KW (g)
Left KW (g)/100 g BW
Right KW (g)
Right KW (g)/100 g BW
8–12 weeks
M
Vehicle
242.6 ± 16.91
1 ± 0.06
0.41 ± 0.01
1 ± 0.06
0.41 ± 0.01
F
Vehicle
164.5 ± 7.17
0.67 ± 0.02
0.41 ± 0.02
0.67 ± 0.02
0.41 ± 0.02
M
A779
221.8 ± 8.16
0.84 ± 0.04
0.38 ± 0.01
0.84 ± 0.04
0.38 ± 0.02
F
A779
171.66 ± 5.32##
0.7 ± 0.03#
0.40 ± 0.01
0.69 ± 0.03#
0.4 ± 0.01
value
0.0001
0.0001
0.52
0.0001
0.58
Age
Gender
Group
BW (g)
Left KW (g)
Left KW (g)/100 g BW
Right KW (g)
Right KW (g)/100 g BW
24–28 weeks
M
Vehicle
319.66 ± 13.72
1.15 ± 0.05
0.36 ± 0.01
1.1 ± 0.05
0.34 ± 0.01
F
Vehicle
211.5 ± 6.87∆∆∆
0.77 ± 0.01 ∆∆∆
0.36 ± 0.01
0.75 ± 0.02∆∆∆
0.35 ± 0.01
M
A779
334.16 ± 17
1.1 2 ± 0.04
0.33 ± 0.01
1.07 ± 0.05
0.32 ± 0.01
F
A779
227.5 ± 7.57$$$
0.87 ± 0.03$$$
0.38 ± 0.01
0.85 ± 0.03$$
0.37 ± 0.02
value
0.0001
0.0001
0.1
0.0001
0.28
Data were expressed as the mean ± standard error of the mean. and represent significant differences in comparison to the 8–12-week male receiving vehicle; # and ## show significant differences in comparison to the 8–12-week male receiving A779; ∆∆∆ shows a significant change compared with the 24–28-week male receiving vehicle; $$ and $$$ reveal significant differences in comparison to the 24–28-week male receiving A779.
