Review Article

Interferon Lambda: A New Sword in Cancer Immunotherapy

Table 1

Clinical indications of IFNs. IFN-α with different trade names is the most indicated in the clinic. IFN-β is mostly indicated for the treatment of relapsing remitting multiple sclerosis. IFN-γ is only indicated for the chronic granulomatous disease. IFN-λ, the new type of IFN, was tested for patients with chronic hepatitis C.

IFN typeIndications in the clinic

IFN-αHairy cell leukemia
Multiple myeloma
Chronic myeloid leukemia
Follicular lymphoma
Cutaneous T lymphoma
Kaposi sarcoma
Melanoma
Renal cell carcinoma
Hepatocellular carcinoma
Condyloma accuminata
Hepatitis B
Hepatitis C

IFN-βMultiple sclerosis

IFN-γChronic granulomatous disease

IFN-λHepatitis C