Transient Decrease in Circulatory Testosterone and Homocysteine Precedes the Development of Metabolic Syndrome Features in Fructose-Fed Sprague Dawley Rats

Figure 2

Plasma insulin responses to an oral glucose load in control and fructose diet-fed rats. (a) 4 weeks. (b) 12 weeks. (c) 24 weeks. (—) Control group. (- - - -) High-fructose-fed group. Values are in mean SE of 8 animals from each group at all time points. at by Student’s -test. Statistical significance of diet, time, and diet time on individual parameters is also analyzed by two-way ANOVA. “S” indicates “significant” (); “NS” indicates “not significant.”

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