The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells

Figure 6

Summary of HE-induced adaptive changes of lipolytic molecules in white adipocytes. ET constantly promotes the expression levels of ATGL and HSL proteins. These conditions are likely to give rise to the stimulation of lipolytic responses through adaptive changes in molecules, such as increases in the anchoring action of AKAP150, higher levels of phosphorylated HSL, and augmentation of the formation of a complex of both HSL/perilipin 1 and ATGL/CGI-58 on the surface of lipid droplet. ↑: upregulation of function and expression levels of each molecule.