Research Article
Differences in In Vitro Disintegration Time among Canadian Brand and Generic Bisphosphonates
Table 1
Amino-bisphosphonate tablet group sample size, lot numbers, and disintegration times.
| | Tablet and dose | Lot numbers | Mean disintegration time in seconds (SDa) | Number of tablets tested |
| | Novo-alendronate 70 mg | A34021 | 12.7 (1.09) | 18 | | Apo-alendronate 70 mg | (L) JD 7416 | 25.7 (5.59) | 20 | | Brand risedronate 35 mg | 425314 | 101.2 (20.56) | 20 | | Brand alendronate 70 mg plus vitamin D 5600 IU | Y 1382 | 378.0 (60.5) | 20 | | Brand alendronate 70 mg | Y1277 and Y1498 | 147.4 (50.47) | 20 |
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SD: standard deviation.
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