Research Article
Whole Body Bone Tissue and Cardiovascular Risk in Rheumatoid Arthritis
Table 1
Comparison between RA and normal patients.
| | | Variable | Normal () | RA () | |
| | | Age (years) | 56.7 (9.7) | 56 (11.4) | ns | | | Menopause | 53 (80.3) | 57 (76%) | ns | | | MPD (years) | 13.1 (9) | 14.3 (7.9) | ns |
| | Bone tissue | wbBTD (g/cm2) | 0.797 (0.093) | 0.763 (0.091) | 0.032 | | wbBTM (kg) | 1.56 (0.16–2.14) | 1.50 (0.82–2.03) | 0.028* | | (sd) | −0.75 (−2.5–1.5) | −0.91 (−3.8–0.9) | 0.015* | | (sd) | −1.1 (1) | −1.5 (1) | 0.035 | | BTP (%) | 2.76 (0.38) | 2.73 (0.37) | ns | | BTDlumbar (g/cm2) | 0.887 (0.159) | 0.857 (0.212) | ns | | (sd) | −0.5 (−3.7–2.8) | −0.7 (−4.4–2.5) | ns* |
| | Anthropometrics | Height (cm) | 159 (5.7) | 160 (6.2) | ns | | Body mass (kg) | 74.5 (13.4) | 69.8 (14) | 0.044 | | WC (cm) | 95.3 (13.6) | 94.3 (12) | ns | | HC (cm) | 107.9 (11.1) | 107.1 (11) | ns | | WHR | 0.88 (0.06) | 0.88 (0.05) | ns | | BMI (kg/m2) | 29.5 (4.9) | 27.3 (4.9) | 0.007 | | CI | 0.60 (0.14) | 0.57 (0.12) | ns |
| | Laboratory | LDL (mg/dL) | 126.5 (38.3) | 131.5 (30.2) | ns | | HDL (mg/dL) | 58.5 (19.8) | 52.2 (11.3) | 0.021 | | TC (mg/dL) | 213.7 (48) | 208.4 (41.1) | ns | | TG (mg/dL) | 110.5 (43–843) | 107.5 (43–258) | ns* | | FPG (mg/dL) | 103.5 (80–210) | 96 (74–243) | 0.001* | | ESR (mm/h) | 20 (3–126) | 28 (4–103) | 0.008* | | CRP (mg/L) | 3.5 (0.2–155) | 6.6 (0.4–183) | 0.024* |
| | Cardiovascular risk | AHT | 42 (63.6%) | 37 (49.3%) | ns | | Anti-AHT treatment | 38 (57.6%) | 43 (57.3%) | ns | | IHD | 20 (30.3%) | 29 (38.7%) | ns | | Antiplatelet | 17 (25.8%) | 25 (33.3%) | ns | | Dyslipidemia | 49 (74.2%) | 67 (89.3%) | 0.019 | | Statins/fibrates | 15 (22.7%) | 26 (34.7%) | ns | | DM | 10 (15.2%) | 3 (4%) | 0.022 | | MetS | 41 (62.1%) | 45 (60%) | ns | | Obesity | 31 (47%) | 18 (24%) | 0.004 | | Inflammation | 24 (36.4%) | 49 (65.3%) | 0.001 | | Smoking | 16 (24.2%) | 7 (9.3%) | 0.017 | | PROCAMqc () | 2.1 (1.4) | 2.7 (1.9) | 0.033 |
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Mann-Whitney test; RA: rheumatoid arthritis; MPD: menopause duration; BT M/D/P: bone tissue mass/density/percent; WC: waist circumference; HC: hip circumference; WHR: waist to hip ratio; BMI: body mass index; CI: conicity index; L/H DL: low/high density lipoproteins; TC: total cholesterol; TG: triglycerides; FPG: fasting plasma glucose; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; AHT: arterial hypertension; IHD: ischemic heart disease; DM: diabetes mellitus; MetS: metabolic syndrome; wb: whole body; qc: quick check; ns: not significant; sd: standard deviation.
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