Evaluation of Bone Mineral Density, Serum Osteocalcin, and Osteopontin Levels in Postmenopausal Women with Type 2 Diabetes Mellitus, with/without Osteoporosis
Table 1
Characteristics of postmenopausal women according to groups.
Parameter mean ± SD
Group I (n = 40)
Group II (n = 60)
Group III (n = 60)
value
Age (years)
58.20 ± 6.01
58.70 ± 5.01
57.91 ± 5.40
0.22
Menopause duration (years)
9.21 ± 4.61
8.92 ± 4.22
9.01 ± 4.40
0.14
T2DM duration (years)
—
7.21 ± 5.3
7.81 ± 5.60
0.12
BMI (kg/m2)
24.90 ± 1.01
26.10 ± 2.61
27.01 ± 2.40
0.19
Total body BMD (g/cm2)
0.91 ± 0.14
0.80 ± 0.10
0.60 ± 0.12
<0.001
BMD LS (g/cm2)
0.98 ± 0.12
0.78 ± 0.10
0.57 ± 0.10
<0.001
BMD FN (g/cm2)
0.61 ± 0.12
0.52 ± 0.14
0.43 ± 0.17
<0.001
T-score LS
0.92 ± 0.12
−2.01 ± 0.90
−3.60 ± 1.80
<0.001
T-score FN
0.83 ± 0.16
−1.98 ± 0.13
−3.94 ± 1.15
<0.001
Fasting glucose (mmol/L)
4.10 ± 1.01
5.01 ± 1.20
8.01 ± 1.41
<0.001
HbA1c (%)
5.01 ± 1.41
7.12 ± 1.60
8.01 ± 2.01
<0.001
OC (ng/mL)
24.40 ± 2.61
24.40 ± 2.32
19.30 ± 1.72
<0.001
OPN (ng/mL)
19.40 ± 2.60
18.10 ± 2.01
14.2 ± 1.40
<0.001
BMI, body mass index; BMD, bone mineral density; LS, lumbar spine; FN, femoral neck; HbA1c, hemoglobin A1c; OC, osteocalcin; OPN, osteopontin. indicates significance.
