Thyroidectomy for Euthyroid Patients with Hashimoto Disease and Persistent Symptoms: An Observational, Postrandomization Study

Table 2

Multivariate logistic regression analysis of collective data from observational groups 2–5 with odds ratios (OR) and 95% confidence intervals to obtain a 5.3 point or higher improvement in General Health (GH) score 18 months after total thyroidectomy.

		GH not improved >5.3 points	GH improved >5.3 points	Univariable OR (95% CI)	Multivariable OR (95% CI)
Sex	Men (%)	3 (20.0)	12 (80.0)	1.0 (reference)	1.0 (reference)
	Women (%)	37 (29.8)	87 (70.2)	0.59 (0.16–2.21),	0.49 (0.12–2.00),
Age	Mean (SD)	51.0 (13.7)	46.8 (12.1)	0.97 (0.95–1.00),	0.97 (0.94–1.01),
Complications	No (%)	29 (27.9)	75 (72.1)	1.0 (reference)	1.0 (reference)
	Yes (%)	11 (31.4)	24 (68.6)	0.84 (0.37–1.94),	0.62 (0.24–1.56),
GH baseline	Mean (SD)	44.7 (25.5)	29.1 (23.4)	0.98 (0.96–0.99),	0.97 (0.96–0.99),
Anti-TPO ab baseline	Mean (SD)	1577.4 (1627.2)	2211.0 (2881.0)	1.00 (1.00-1.00),	1.00 (1.00-1.00),