Impact of Recipient and Donor Obesity Match on the Outcomes of Liver Transplantation: All Matches Are Not Perfect

Table 2

Multivariable Cox proportional hazards regression of survival after liver transplantation ( = 40,478).

Covariates	HR	95% CI
Male recipient	0.94	(0.90, 0.99)	0.010
Recipient age	1.02	(1.01, 1.02)	<0.001
Recipient race
White	Ref.
Black	1.28	(1.20, 1.37)	<0.001
Other	0.84	(0.79, 0.89)	<0.001
Etiology
Viral	Ref.
Cryptogenic	0.73	(0.67, 0.80)	<0.001
Autoimmune	0.67	(0.61, 0.74)	<0.001
NASH	0.72	(0.65, 0.80)	<0.001
Alcoholic	0.82	(0.77, 0.87)	<0.001
HCC	1.13	(1.06, 1.20)	<0.001
Other	1.12	(1.05, 1.20)	0.001
Recipient diabetes	1.21	(1.16, 1.27)	<0.001
Acute rejection before discharge	1.14	(1.05, 1.24)	0.001
PVT at transplantation	1.23	(1.15, 1.33)	<0.001
MELD score at LT	1.02	(1.02, 1.03)	<0.001
Male donor	1.01	(0.96, 1.05)	0.790
Donor age	1.01	(1.01, 1.01)	<0.001
Donor race
White	Ref.
Black	0.99	(0.94, 1.06)	0.845
Other	1.17	(1.11, 1.24)	<0.001
Donor diabetes	1.09	(1.02, 1.17)	0.010
Donor hypertension	0.99	(0.94, 1.05)	0.845
Donor CMV positive	1.03	(0.98, 1.08)	0.224
Donor HBV positive	1.06	(0.97, 1.16)	0.191
Donor HCV positive	1.16	(1.04, 1.29)	0.008
Cold ischemia time	1.01	(1.01, 1.02)	<0.001
BMI of recipient (R) and donor (D)
Nonobese R, nonobese D	Ref.
Nonobese R, obese D	0.98	(0.92, 1.04)	0.547
Obese R, nonobese D	0.91	(0.86, 0.96)	<0.001
Obese R, obese D	0.93	(0.86, 1.00)	0.042

Obesity defined as BMI 30 kg/m².