Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells
Figure 3
Regulation of NAMPT and COX2 expressions by periodontopathogens. NAMPT expression in PDL cells from 3 donors in response to various periodontopathogens (OD: 0.1; P. gingivalis, Pg; T. denticola, Td; T. forsythia, Tf; A. actinomycetemcomitans, Aa) at 1 d (a) and 3 d (b). Stimulation of NAMPT expression in PDL cells from 3 donors by various concentrations of P. gingivalis (OD: 0.025, 0.050, and 0.100) at 1 d (c) and 3 d (d). COX2 expression in PDL cells from 3 donors in response to various periodontopathogens (OD: 0.1; P. gingivalis, Pg; T. denticola, Td; T. forsythia, Tf; A. actinomycetemcomitans, Aa) at 1 d (e) and 3 d (f). Stimulation of COX2 expression in PDL cells from 3 donors by various concentrations of P. gingivalis (OD: 0.025, 0.050, and 0.100) at 1 d (g) and 3 d (h). All experiments were performed in triplicate and repeated at least twice. Mean ± SEM; *significantly () different from P. gingivalis-untreated cells (control).
