Research Article
Early Transcriptional Changes Induced by Wnt/β-Catenin Signaling in Hippocampal Neurons
Table 1
Top 20 nominal significant Wnt3a-upregulated genes in hippocampal neurons.
| Symbol ID | FC | value | Wnt pathway | References |
| Fam84a | 2.4 | 2.2 × 10−6 | — | — | Notum | 14.1 | 1.5 × 10−5 | Wnt target gene | [45] | Lef1 | 2.1 | 1.7 × 10−5 | Wnt target gene | [46] | Axin2 | 3.5 | 1.2 × 10−4 | Wnt target gene | [47] | Prkg2 | 2.7 | 1.4 × 10−4 | Functional | [48] | Cxcl3 | 4.6 | 5.2 × 10−4 | Wnt target gene | [49] | Ahr | 2.1 | 1.0 × 10−3 | Wnt target gene | [50] | Stk32a | 1.8 | 1.3 × 10−3 | — | — | Itga9 | 2.0 | 1.7 × 10−3 | — | — | Tnfresf19 | 2.4 | 1.8 × 10−3 | Wnt target gene | [51] | Tmem72 | 1.7 | 2.0 × 10−3 | — | — | Fras1 | 1.9 | 2.2 × 10−3 | — | — | Fam167a | 1.8 | 2.2 × 10−3 | — | — | Gata2 | 2.8 | 2.3 × 10−3 | Wnt target gene | [52] | Id2 | 1.3 | 3.0 × 10−3 | Wnt target gene | [53] | Msx2 | 2.1 | 3.9 × 10−3 | Wnt target gene | [54] | Sp5 | 10.3 | 4.2 × 10−3 | Wnt target gene | [55] | Cd83 | 2.1 | 4.4 × 10−3 | — | — | Cgnl1 | 1.5 | 4.9 × 10−3 | — | — | Hunk | 1.5 | 5.3 × 10−3 | Wnt target gene | [56] |
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Functional: known to modulate Wnt pathway transcriptional activity. FC: fold change.
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