Research Article
XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma
Table 3
Univariate and multivariate analyses of the cytoplasmic EIF1AX expression and clinical-pathological factors on survival.
| Variables | Univariate | Multivariate | HR (95% CI) | | HR (95% CI) | |
| Cytoplasmic EIF1AX expression (negative vs. positive) | 26.313 (0.064-10778.959) | 0.287 | | | Cytoplasmic EIF1AX expression (low vs. high) | 3.325 (1.134-9.746) | 0.029 | | | Histological type (endometroid vs. serous) | 8.092 (2.790-23.470) | <0.001 | 5.416 (1.755-17.022) | 0.003 | Histological grade (low vs. high) | 7.722 (2.173-27.442) | 0.002 | | | FIGO stage(I + II vs. III + IV) | 6.112 (2.183-17.114) | 0.001 | | | Invasive depth (<1/2 vs. ≥1/2) | 5.601 (1.780-17.627) | 0.003 | | | Lymphovascular invasion (no vs. yes) | 2.034 (0.721-5.740) | 0.180 | | | Ki67 index (low vs. high) | 7.179 (2.283-22.575) | 0.001 | 5.252 (1.611-17.117) | 0.006 |
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