BACE1 Inhibition Utilizing Organic Compounds Holds Promise as a Potential Treatment for Alzheimer’s and Parkinson’s Diseases

Figure 1

By plotting the compounds’ ID on the x-axis and their estimated binding energies (kcal/mol) on the Y-axis, the study presented the ΔG_binding values between the most potent herbal inhibitors, positive control compounds, and the BACE1 active site. The blue diamonds represented control compounds, while the yellow spots depicted the top-ranked inhibitors in the study. BACE1, β-site amyloid precursor protein cleaving enzyme 1.