Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro
Table 2
Concentrations of major metabolites of various extracts of I. obliquus and microalgae.
Compound
m/z
RT (min)
Concentration (mg/g extract)
MH-E1
MH-H2O
MH-E1-SF
MH-SFE1b
MH-SFE1c
GL-E1
GLE1-CF
GLE1-CF-SF
Betulinic acid
455.2
3.57
2.99
0.01
1.56
15.2
1.21
ND
ND
ND
Trametenolic acid
455.2
3.67
37.49
0.26
21.46
334.4
17.48
ND
ND
ND
p-Hydroxy benzoic acid
137.0
3.9
7.32
2.63
1.81
0.57
6.84
0.09
0.07
0.80
Cinnamic acid
146.9
7.4
0.00
0.35
0.23
0.00
0.00
0.00
0.17
0.00
Dihydro ferulic acid
195.0
8.25
0.59
8.33
0.95
0.91
0.55
0.66
0.41
5.90
Sinapic acid
223.0
5.4
0.13
0.14
0.01
0.01
0.04
0.00
0.00
0.01
Protocatechuic acid
152.8
2.5
0.86
0.30
0.36
0.00
0.13
0.00
0.08
0.03
Caffeic acid
179.0
4.3
0.08
0.03
0.02
0.00
0.12
0.00
0.00
0.01
Syringic acid
197.0
3.9
13.98
109.8
11.60
0.03
6.31
0.03
0.27
0.15
Taxifolin
303.0
0.95
0.08
0.17
0.02
0.03
0.09
0.32
0.01
0.36
Catechin
288.7
3.4
0.42
9.16
3.72
0.00
0.00
0.00
0.00
0.00
Quercetin
300.7
6.8
0.57
1.67
0.39
0.00
0.00
0.00
0.00
0.00
ND, not detected; m/z, mass/charge used for the single ion monitoring mode; and RT, retention time. For the abbreviations of the extracts, please refer to Table 1.
