Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro
Table 3
IC50 values (µg/mL) of various extracts of I. Obliquus and microalgae against mammalian cancer cell lines.
Extracts
Mammalian cell lines
MCF7
HepG2
HOS
D-17
DH-82
I. obliquus
MH-E1
769 ± 166
540 ± 7.9
219 ± 37.2
208 ± 8.6
196 ± 24.5
MH-H2O
>1,000
>1,000
>1,000
934 ± 262
>1,000
MH-E1-SF
187 ± 7.07
115 ± 31.6
125 ± 10.7
172 ± 12.0
134 ± 29.3
MH-SFE1b
340 ± 23.8
559 ± 80.5
313 ± 21.0
342 ± 52.1
358 ± 31.9
MH-SFE1c
182 ± 43.0
640 ± 173
262 ± 12.2
235 ± 15.1
150 ± 9.4
Microalgae
GLE1
445 ± 22.9
>1,000
527 ± 3.9
465 ± 90.3
396 ± 27.3
GLE1-CF
322 ± 37.9
501 ± 58.6
281 ± 15.0
347 ± 53.2
246 ± 10.9
GLE1-CF-SF
199 ± 52.4
231 ± 13.2
108 ± 9.1
131 ± 16.6
131 ± 1.9
For the abbreviations of the extracts, please refer to Table 1. MCF-7, human breast epithelial adenocarcinoma; HepG2, human hepatocellular carcinoma; HOS, human osteosarcoma; D-17, canine osteosarcoma; and DH-82, canine histiocytosis.
