Research Article

Eosinophil Counts in Mucosal Biopsies of the Ileum and Colon: Interobserver Variance Affects Diagnostic Accuracy

Table 2

Eosinophil counts of each pathologist for each anatomic site of each patient. Values shown are mean ± SD from 5 HPF and normalized (Table 1). Asterisk: Investigator counted 3 HPF as “>100” each, one as 70 and one as 90. p = “asymptotic significance” - Friedman test p-value.

Investigator 1Investigator 2Investigator 3Investigator 4Investigator 5Investigator 6p Value

Pat
1
Ileum49±8,44±1,93±0,720±8,05±1,719±7,2< 0.001
Flexure50±14,210±4,11±1,113±8,24±1,230±5,5 = 0.001
Rectum20±6,55±1,420±0,53±1,72±1,45±3,1< 0.001

Pat
2
Ileum48±21,15±2,77±3,14±2,62±1,224±11,7= 0.001
Flexure328±1,425±6,413±1,4(70)70±6,3140±19,6< 0.001
Rectum78±12,84±1,24±4,120±14,90±0,437±18,3< 0.001

Pat
3
Ileum54±21,15±4,18±1,47±4,02±0,615±6,5< 0.001
Flexure60±9,18±1,929±2,012±7,04±1,923±3,2< 0.001
Rectum27±5,65±1,93±5,23±2,11±1,26±2,9< 0.001

Pat
4
Ileum11±2,71±0,56±1,24±3,03±1,74±1,3< 0.05
Flexure30±12,86±3,01±2,07±3,66±1,622±6,0< 0.05
Rectum6±2,21±0,53±0,42±2,70±0,53±1,5< 0.05

Pat
5
Ileum89±14,83±1,23±1,36±1,77±3,123±9,7= 0.001
Flexure42±13,07±1,41±1,06±2,87±2,511±1,4= 0.001
Rectum7±3,23±0,93±0,81±1,41±0,94±1,1< 0.001

Pat
6
Ileum19±2,34±2,18±1,71±1,60±0,413±2,3< 0.001
Flexure101±10,013±5,21±1,716±3,74±2,347±12,6< 0.001
Rectum3±0,62±1,04±0,51±1,41±0,54±1,5= 0.001

Pat
7
Ileum68±14,410±3,75±1,83±1,41±0,653±12,1= 0.001
Flexure34±1,49±3,42±1,96±2,92±1,529±6,8< 0.001
Rectum28±21,16±1,72±0,95±3,91±0,65±2,5= 0.001

Pat
8
Ileum31±6,75±1,03±1,04±2,32±1,118±6,7= 0.001
Flexure34±8,72±0,61±1,56±3,24±2,019±7,4= 0.001
Rectum7±3,23±1,02±0,76±2,61±0,55±1,3= 0.001

Pat
9
Ileum9±2,73±1,24±0,71±1,71±0,88±2,5< 0.001
Flexure33±8,86±1,21±1,23±2,92±0,833±6,3< 0.001
Rectum5±0,62±1,31±0,53±2,10±0,54±1,0< 0.05

Pat
10
Ileum28±10,16±1,43±1,06±2,21±1,211±10,2< 0.001
Flexure21±4,65±1,61±0,77±3,43±1,78±2,6<0.001
Rectum2±0,41±0,53±0,52±1,00±0,41±0,7< 0.05