Abnormal Circadian Modification of A<i>δ</i>-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome

<div>Laser-evoked potentials (LEP) obtained after foot and hand stimulation in an RLS patient (a) and a control subject (b). The figure shows, in RLS patient, that both A<i>δ</i>-N1 and A<i>δ</i>-N2-P2 amplitudes after foot stimulation are increased during night when compared to daytime recordings. Conversely, LEP amplitude after hand stimulation results in unmodified night and day stimulation. In control subject, LEP amplitudes are substantially unchanged in two sessions after foot and hand stimulation.</div>

Pain Research and Management

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Figure 1: Abnormal Circadian Modification of A<i>δ</i>-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome 

Pain Research and Management

Abnormal Circadian Modification of Aδ-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome

Figure 1