Research Article

Factors Associated with Longitudinal Changes in Mammographic Density in a Multiethnic Breast Screening Cohort of Postmenopausal Women

Table 2

Baseline characteristics of patients who exhibited an increase or no change in the BI-RADS density category (among those with baseline BI-RADS A, B, or C).

Increased (N = 227)No change (N = 2644)Total (N = 2871) value

Age at baseline0.27
 Mean (SD)62.3 (9.38)61.6 (8.69)61.70 (8.74)
 Range39–8334–9234–92
Race/ethnicity0.016
 Non-Hispanic White111 (48.9%)1375 (52.0%)1486 (51.8%)
 Hispanic45 (19.8%)674 (25.5%)719 (25.0%)
 Non-Hispanic Asian56 (24.7%)454 (17.2%)510 (17.8%)
 Non-Hispanic other/unknown15 (6.6%)141 (5.3%)156 (5.4%)
Menarche age0.563
 <1247 (21.3%)482 (18.4%)529 (18.7%)
 12 to 13105 (47.5%)1309 (50.1%)1414 (49.9%)
 >1469 (31.2%)824 (31.5%)893 (31.5%)
Parity0.925
 No40 (17.7%)473 (18.0%)513 (17.9%)
 Yes186 (82.3%)2162 (82.0%)2348 (82.1%)
Age at first birth0.227
 <2021 (11.3%)345 (16.0%)366 (15.6%)
 20 to 30128 (68.8%)1388 (64.4%)1516 (64.8%)
 >3037 (19.9%)421 (19.5%)458 (19.6%)
Menopause age0.437
 <55200 (88.9%)2300 (87.1%)2500 (87.2%)
 55 and older25 (11.1%)341 (12.9%)366 (12.8%)
Years since menopause0.238
 Less than 538 (17.0%)533 (20.3%)571 (20.0%)
 5 or more186 (83.0%)2099 (79.7%)2285 (80.0%)
Current hormone use0.804
 No191 (84.1%)2241 (84.8%)2432 (84.7%)
 Yes36 (15.9%)403 (15.2%)439 (15.3%)
BMI category (race-specific)0.211
 Not overweight/obese100 (44.2%)1023 (39.4%)1123 (39.8%)
 Overweight76 (33.6%)872 (33.6%)948 (33.6%)
 Obese50 (22.1%)702 (27.0%)752 (26.6%)
Smoking0.493
 Never115 (79.3%)1389 (75.9%)1504 (76.2%)
 Former26 (17.9%)355 (19.4%)381 (19.3%)
 Current4 (2.8%)85 (4.6%)89 (4.5%)
Physical activity0.244
 None44 (43.6%)430 (38.0%)474 (38.5%)
 <150 min mild, moderate, or strenuous activity per week33 (32.7%)342 (30.2%)375 (30.4%)
 At least 150 min mild, moderate, or strenuous activity per week24 (23.8%)359 (31.7%)383 (31.1%)
Alcohol consumption0.101
 Yes98 (43.6%)1293 (49.3%)1391 (48.8%)
 No127 (56.4%)1332 (50.7%)1459 (51.2%)