Research Article

Factors Associated with Longitudinal Changes in Mammographic Density in a Multiethnic Breast Screening Cohort of Postmenopausal Women

Table 3

Baseline characteristics of patients who exhibited a decrease or no change in the BI-RADS density category (among those with baseline BI-RADS B, C, or D).

Decreased (N = 268)No change (N = 2560)Total (N = 2828)p value

Age at baseline0.003
 Mean (SD)59.5 (9.1)61.2 (8.7)61.0 (8.7)
 Range37–8933–9233–92
Race/ethnicity0.062
 Non-Hispanic White162 (60.4%)1327 (51.8%)1489 (52.7%)
 Hispanic51 (19.0%)599 (23.4%)650 (23.0%)
 Non-Hispanic Asian46 (17.2%)517 (20.2%)563 (19.9%)
 Non-Hispanic other/unknown9 (3.4%)117 (4.6%)126 (4.5%)
Menarche age0.278
 <1237 (14.0%)417 (16.5%)454 (16.2%)
 12 to 13147 (55.5%)1278 (50.5%)1425 (50.9%)
 >1481 (30.6%)837 (33.1%)918 (32.8%)
Parity0.437
 No56 (20.9%)483 (18.9%)539 (19.1%)
 Yes212 (79.1%)2068 (81.1%)2280 (80.9%)
Age at first birth0.662
 <2035 (16.5%)297 (14.4%)332 (14.6%)
 20 to 30130 (61.3%)1319 (64.0%)1449 (63.7%)
 >3047 (22.2%)445 (21.6%)492 (21.6%)
Menopause age0.025
 <55246 (91.8%)2224 (87.0%)2470 (87.5%)
 55 and older22 (8.2%)332 (13.0%)354 (12.5%)
Years since menopause0.844
 Less than 561 (23.0%)573 (22.5%)634 (22.5%)
 5 or more204 (77.0%)1975 (77.5%)2179 (77.5%)
Current hormone use0.483
 No219 (81.7%)2135 (83.4%)2354 (83.2%)
 Yes49 (18.3%)425 (16.6%)474 (16.8%)
BMI category (race-specific)0.574
 Not overweight/obese132 (50.0%)1173 (46.6%)1305 (46.9%)
 Overweight82 (31.1%)827 (32.9%)909 (32.7%)
 Obese50 (18.9%)516 (20.5%)566 (20.4%)
Smoking0.234
 Never151 (77.4%)1391 (77.1%)1542 (77.2%)
 Former40 (20.5%)331 (18.4%)371 (18.6%)
 Current4 (2.1%)81 (4.5%)85 (4.3%)
Physical activity0.91
 None37 (34.3%)393 (35.7%)430 (35.6%)
 <150 min mild, moderate, or strenuous activity per week35 (32.4%)335 (30.5%)370 (30.6%)
 At least 150 min mild, moderate, or strenuous activity per week36 (33.3%)372 (33.8%)408 (33.8%)
Alcohol consumption0.538
 Yes141 (52.8%)1292 (50.8%)1433 (51.0%)
 No126 (47.2%)1250 (49.2%)1376 (49.0%)