Human-Mimic Submuscular and Premuscular Irradiated Rat Model: Histologic Characteristics of the Capsule Tissue in Contact with the Breast Implant

Table 1

Comparison of the capsule characteristics between the submuscular and premuscular groups.

	Submuscular	Premuscular	value
Capsule in ADM
Capsule thickness (μm)	143.8 ± 61.5	62.0 ± 50.5	0.026
Inflammatory cell count	70.1 ± 60.6	62.8 ± 29.8	0.937
α-SMA (%)	10.0 ± 5.4	29.5 ± 9.3	0.004
CD31 vessels	1.17 ± 0.9	5.0 ± 2.7	0.004
Capsule in the chest wall
Capsule thickness (μm)	328.3 ± 177.6	300.17 ± 226.8	0.485
Inflammatory cell count	113.1 ± 50.6	228.8 ± 109.2	0.041
α-SMA (%)	32.9 ± 13.6	46.6 ± 14.4	0.132
CD31 vessels	20.8 ± 14.9	32.5 ± 9.5	0.065