Table 6: KEGG pathways containing the predicted targets of the differentially expressed miRNAs. Pathway-Express analysis identified the KEGG molecular pathways affected by the predicted targets of the differentially expressed miRNAs. 𝑃 < . 0 5 .

RankPathway nameGenes in pathwayInput genes in pathwayPathway genes on chip 𝑃 -value

1MAPK signaling pathway2721031973.23E−08
2Axon guidance129671133.23E−08
3Melanogenesis10248748.60E−08
4Pathways in cancer3301192452.27E−07
5Regulation of actin cytoskeleton217781582.31E−05
6Focal adhesion203751502.31E−05
7Wnt signaling pathway152631271.60E−04
8Glioma6530502.94E−04
9GnRH signaling pathway10336654.86E−04
10Renal cell carcinoma6934615.92E−04
11Insulin signaling pathway13849987.02E−04
12Adherens junction7834627.65E−04
13TGF-beta signaling pathway8738728.49E−04
14Prostate cancer903668.0011
15ECM-receptor interaction843055.0016
16Phosphatidylinositol signaling system763055.0016
17Calcium signaling pathway18254115.0016
18Colorectal cancer843670.0018
19Long-term potentiation733158.0018
20Adipocytokine signaling pathway672750.0032
21ErbB signaling pathway873469.0056
22Pancreatic cancer723059.0056
23Gap junction963367.0063
24Type II diabetes mellitus451831.0069
25Small cell lung cancer863061.0095
26Thyroid cancer291423.0111
27Ubiquitin mediated proteolysis1384294.0145
28Long-term depression752449.0225
29Non-small cell lung cancer542039.0225
30Acute myeloid leukemia592245.0304
31Melanoma712553.0323
32Cardiac muscle contraction872041.0402
33Chronic myeloid leukemia752862.0410