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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 157458, 7 pages
http://dx.doi.org/10.1155/2011/157458
Research Article

Novel Concept of Motor Functional Analysis for Spinal Cord Injury in Adult Mice

1Department of Physiology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
2Department of Neurosurgery, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan
3Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
4Department of Rehabilitation Medicine, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan

Received 9 September 2010; Accepted 2 December 2010

Academic Editor: Monica Fedele

Copyright © 2011 Munehisa Shinozaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. M. Basso, M. S. Beattie, and J. C. Bresnahan, “A sensitive and reliable locomotor rating scale for open field testing in rats,” Journal of Neurotrauma, vol. 12, no. 1, pp. 1–21, 1995. View at Scopus
  2. D. M. Basso, L. C. Fisher, A. J. Anderson, L. B. Jakeman, D. M. McTigue, and P. G. Popovich, “Basso mouse scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains,” Journal of Neurotrauma, vol. 23, no. 5, pp. 635–659, 2006. View at Scopus
  3. J. E. Beare, J. R. Morehouse, W. H. Devries, G. U. Enzmann, D. A. Burke, D. S. K. Magnuson, and S. R. Whittemore, “Gait analysis in normal and spinal contused mice using the treadscan system,” Journal of Neurotrauma, vol. 26, no. 11, pp. 2045–2056, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. M. Bervar, “Video analysis of standing—an alternative footprint analysis to assess functional loss following injury to the rat sciatic nerve,” Journal of Neuroscience Methods, vol. 102, no. 2, pp. 109–116, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. L. de Medinaceli, W. J. Freed, and R. J. Wyatt, “An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks,” Experimental Neurology, vol. 77, no. 3, pp. 634–643, 1982. View at Scopus
  6. M. G. Fehlings, C. H. Tator, R. D. Linden, and I. R. Piper, “Motor and somatosensory evoked potentials recorded from the rat,” Electroencephalography and Clinical Neurophysiology, vol. 69, no. 1, pp. 65–78, 1988. View at Scopus
  7. L. B. Goldstein and J. N. Davis, “Beam-walking in rats: studies towards developing an animal model of functional recovery after brain injury,” Journal of Neuroscience Methods, vol. 31, no. 2, pp. 101–107, 1990. View at Publisher · View at Google Scholar · View at Scopus
  8. J. S. Soblosky, L. L. Colgin, D. Chorney-Lane, J. F. Davidson, and M. E. Carey, “Ladder beam and camera video recording system for evaluating forelimb and hindlimb deficits after sensorimotor cortex injury in rats,” Journal of Neuroscience Methods, vol. 78, no. 1-2, pp. 75–83, 1997. View at Publisher · View at Google Scholar · View at Scopus
  9. Y. Mikami, M. Toda, M. Watanabe, M. Nakamura, Y. Toyama, and Y. Kawakami, “A simple and reliable behavioral analysis of locomotor function after spinal cord injury in mice: technical note,” Journal of Neurosurgery, vol. 97, no. 1, pp. 142–147, 2002. View at Scopus
  10. W. B. J. Cafferty, N. J. Gardiner, P. Das, J. Qiu, S. B. McMahon, and S. W. N. Thompson, “Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice,” Journal of Neuroscience, vol. 24, no. 18, pp. 4432–4443, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. Y. Mikami, H. Okano, and H. Okano, “Implantation of dendritic cells in injured adult spinal cord results in activation of endogenous neural stem/progenitor cells leading to de novo neurogenesis and functional recovery,” Journal of Neuroscience Research, vol. 76, no. 4, pp. 453–465, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. K. Kawahats and M. Miyashita, “Electromyogram premotion silent period and tension development in human muscle,” Experimental Neurology, vol. 82, no. 2, pp. 287–302, 1983. View at Scopus
  13. S. Rossignol, “Neural control of stereotypic limb movements,” in Handbook of Physiology, L. B. Rowell and J. T. Sheperd, Eds., pp. 173–216, Oxford University Press, New York, NY, USA, 1996.
  14. H. Gee, “Animal guidelines,” Nature, vol. 334, no. 6177, p. 7, 1988. View at Scopus
  15. A. S. Rivlin and C. H. Tator, “Objective clinical assessment of motor function after experimental spinal cord injury in the rat,” Journal of Neurosurgery, vol. 47, no. 4, pp. 577–581, 1977. View at Scopus