Animal Models of Human Pathology

• Animal Models of Human Pathology, Monica Fedele, Oreste Gualillo, and Andrea Vecchione
  Volume 2011 (2011), Article ID 764618, 1 page
• Guillain-Barré Syndrome Animal Model: The First Proof of Molecular Mimicry in Human Autoimmune Disorder, Nortina Shahrizaila and Nobuhiro Yuki
  Volume 2011 (2011), Article ID 829129, 5 pages
• Genetic Rodent Models of Amyotrophic Lateral Sclerosis, L. Van Den Bosch
  Volume 2011 (2011), Article ID 348765, 11 pages
• Muscle Atrophy and Motor Neuron Degeneration in Human NEDL1 Transgenic Mice, Lin Zhang, Seiki Haraguchi, Tadayuki Koda, Kenji Hashimoto, and Akira Nakagawara
  Volume 2011 (2011), Article ID 831092, 7 pages
• Role of PIR-B in Autoimmune Glomerulonephritis, Toshiyuki Takai, Akira Nakamura, and Shota Endo
  Volume 2011 (2011), Article ID 275302, 9 pages
• Analysis of the Pathogenesis of Experimental Autoimmune Optic Neuritis, Takeshi Kezuka, Yoshihiko Usui, and Hiroshi Goto
  Volume 2011 (2011), Article ID 294046, 5 pages
• Current Concepts: Mouse Models of Sjögren's Syndrome, Tegan N. Lavoie, Byung Ha Lee, and Cuong Q. Nguyen
  Volume 2011 (2011), Article ID 549107, 14 pages
• Dysfunction of Lacrimal and Salivary Glands in Sjögren's Syndrome: Nonimmunologic Injury in Preinflammatory Phase and Mouse Model, Toshiharu Hayashi
  Volume 2011 (2011), Article ID 407031, 15 pages
• Loss of the NHE2 Na⁺/H⁺ Exchanger in Mice Results in Dilation of Folliculo-Stellate Cell Canaliculi, Marian L. Miller, Anastasia Andringa, Patrick J. Schultheis, and Gary E. Shull
  Volume 2011 (2011), Article ID 510827, 14 pages
• Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications, Akinori Nakamura and Shin'ichi Takeda
  Volume 2011 (2011), Article ID 184393, 8 pages
• Gait Disturbances in Dystrophic Hamsters, Thomas G. Hampton, Ajit Kale, Ivo Amende, Wenlong Tang, Scott McCue, Hemmi N. Bhagavan, and Case G. VanDongen
  Volume 2011 (2011), Article ID 235354, 8 pages
• Animal Models for Periodontal Disease, Helieh S. Oz and David A. Puleo
  Volume 2011 (2011), Article ID 754857, 8 pages
• The Animal Model of Spinal Cord Injury as an Experimental Pain Model, Aya Nakae, Kunihiro Nakai, Kenji Yano, Ko Hosokawa, Masahiko Shibata, and Takashi Mashimo
  Volume 2011 (2011), Article ID 939023, 11 pages
• Novel Concept of Motor Functional Analysis for Spinal Cord Injury in Adult Mice, Munehisa Shinozaki, Yuichiro Takahashi, Masahiko Mukaino, Nobuhito Saito, Yoshiaki Toyama, Hideyuki Okano, and Masaya Nakamura
  Volume 2011 (2011), Article ID 157458, 7 pages
• Experimental Trauma Models: An Update, Michael Frink, Hagen Andruszkow, Christian Zeckey, Christian Krettek, and Frank Hildebrand
  Volume 2011 (2011), Article ID 797383, 15 pages
• Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis, Susanne Drechsler, Katrin M. Weixelbaumer, Heinz Redl, Martijn van Griensven, Soheyl Bahrami, and Marcin F. Osuchowski
  Volume 2011 (2011), Article ID 357926, 12 pages
• Animal Models of Typical Heterotopic Ossification, Lixin Kan and John A. Kessler
  Volume 2011 (2011), Article ID 309287, 8 pages
• Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy, Brad Bolon, Marina Stolina, Caroline King, Scot Middleton, Jill Gasser, Debra Zack, and Ulrich Feige
  Volume 2011 (2011), Article ID 569068, 21 pages
• Hydrodynamic Delivery of Chitosan-Folate-DNA Nanoparticles in Rats with Adjuvant-Induced Arthritis, Qin Shi, Huijie Wang, Covi Tran, Xingping Qiu, Françoise M. Winnik, Xiaoling Zhang, Kerong Dai, Mohamed Benderdour, and Julio C. Fernandes
  Volume 2011 (2011), Article ID 148763, 9 pages
• Experimental Model of Zymosan-Induced Arthritis in the Rat Temporomandibular Joint: Role of Nitric Oxide and Neutrophils, Hellíada Vasconcelos Chaves, Ronaldo de Albuquerque Ribeiro, André Mattos Brito de Souza, Antonio Alfredo Rodrigues e Silva, Antoniella Souza Gomes, Mariana Lima Vale, Mirna Marques Bezerra, and Gerly Anne de Castro Brito
  Volume 2011 (2011), Article ID 707985, 11 pages
• Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats, Fei Huang, Min Zhang, Yong-Jin Chen, Qiang Li, and An-Zhen Wu
  Volume 2011 (2011), Article ID 720603, 8 pages
• Evaluation of Itch by Using NC/NgaTnd Mice: A Model of Human Atopic Dermatitis, Akane Tanaka and Hiroshi Matsuda
  Volume 2011 (2011), Article ID 790436, 5 pages
• Surgical Approaches to Create Murine Models of Human Wound Healing, Victor W. Wong, Michael Sorkin, Jason P. Glotzbach, Michael T. Longaker, and Geoffrey C. Gurtner
  Volume 2011 (2011), Article ID 969618, 8 pages
• Collagen-Based Films Containing Liposome-Loaded Usnic Acid as Dressing for Dermal Burn Healing, Paula S. Nunes, Ricardo L. C. Albuquerque-Júnior, Danielle R. R. Cavalcante, Marx D. M. Dantas, Juliana C. Cardoso, Marília S. Bezerra, Jamille C. C. Souza, Mairim Russo Serafini, Lucindo J. Quitans-Jr, Leonardo R. Bonjardim, and Adriano A. S. Araújo
  Volume 2011 (2011), Article ID 761593, 9 pages
• In Vivo Imaging of Particle-Induced Inflammation and Osteolysis in the Calvariae of NF B/Luciferase Transgenic Mice, Kunihiko Takahashi, Shin Onodera, Harukazu Tohyama, Hyuck Joon Kwon, Ken-ichi Honma, and Kazunori Yasuda
  Volume 2011 (2011), Article ID 727063, 8 pages
• Joint Inflammation and Early Degeneration Induced by High-Force Reaching Are Attenuated by Ibuprofen in an Animal Model of Work-Related Musculoskeletal Disorder, Jeffrey B. Driban, Ann E. Barr, Mamta Amin, Michael R. Sitler, and Mary F. Barbe
  Volume 2011 (2011), Article ID 691412, 17 pages
• A Transgenic Mouse Model for Studying the Role of the Parathyroid Hormone-Related Protein System in Renal Injury, Ricardo J. Bosch, Arantxa Ortega, Adriana Izquierdo, Ignacio Arribas, Jordi Bover, and Pedro Esbrit
  Volume 2011 (2011), Article ID 290874, 7 pages
• Approaching Biomarkers of Membranous Nephropathy from a Murine Model to Human Disease, Chia-Chao Wu, Jin-Shuen Chen, Ching-Feng Huang, Chun-Chi Chen, Kuo-Chen Lu, Pauling Chu, Huey-Kang Sytwu, and Yuh-Feng Lin
  Volume 2011 (2011), Article ID 581928, 11 pages
• Intravesical Dimethyl Sulfoxide Inhibits Acute and Chronic Bladder Inflammation in Transgenic Experimental Autoimmune Cystitis Models, Ronald Kim, Wujiang Liu, Xiaohong Chen, Karl J. Kreder, and Yi Luo
  Volume 2011 (2011), Article ID 937061, 9 pages
• Murine Models of Systemic Lupus Erythematosus, Daniel Perry, Allison Sang, Yiming Yin, Ying-Yi Zheng, and Laurence Morel
  Volume 2011 (2011), Article ID 271694, 19 pages
• The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus, Maria Gulinello and Chaim Putterman
  Volume 2011 (2011), Article ID 207504, 15 pages
• Kainic Acid-Induced Neurodegenerative Model: Potentials and Limitations, Xiang-Yu Zheng, Hong-Liang Zhang, Qi Luo, and Jie Zhu
  Volume 2011 (2011), Article ID 457079, 10 pages
• Presenilin-2 Mutation Causes Early Amyloid Accumulation and Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease, Toshihiko Toda, Yoshihiro Noda, Genzo Ito, Masahiro Maeda, and Takahiko Shimizu
  Volume 2011 (2011), Article ID 617974, 12 pages
• A Missense Mutation in Canine CLN6 in an Australian Shepherd with Neuronal Ceroid Lipofuscinosis, Martin L. Katz, Fabiana H. Farias, Douglas N. Sanders, Rong Zeng, Shahnawaz Khan, Gary S. Johnson, and Dennis P. O'Brien
  Volume 2011 (2011), Article ID 198042, 6 pages
• A Novel Animal Model of Hippocampal Cognitive Deficits, Slow Neurodegeneration, and Neuroregeneration, Simon C. Spanswick, Hugo Lehmann, and Robert J. Sutherland
  Volume 2011 (2011), Article ID 527201, 12 pages
• Perinatal Hypoxic-Ischemic Encephalopathy, Ming-Chi Lai and San-Nan Yang
  Volume 2011 (2011), Article ID 609813, 6 pages
• The Development and the Use of Experimental Animal Models to Study the Underlying Mechanisms of CA Formation, Tomohiro Aoki and Masaki Nishimura
  Volume 2011 (2011), Article ID 535921, 10 pages
• Middle Cerebral Artery Occlusion Model in Rodents: Methods and Potential Pitfalls, Fudong Liu and Louise D. McCullough
  Volume 2011 (2011), Article ID 464701, 9 pages
• Blood-Oxygenation-Level-Dependent-(BOLD-) Based R2^′ MRI Study in Monkey Model of Reversible Middle Cerebral Artery Occlusion, Jing Zhang, Ying-min Chen, and Yun-ting Zhang
  Volume 2011 (2011), Article ID 318346, 8 pages
• Phosphocreatine Preconditioning Attenuates Apoptosis in Ischemia-Reperfusion Injury of Rat Brain, Ling-Hua Tang, Zhong-Yuan Xia, Bo Zhao, Xiao-Dong Wei, Tao Luo, and Qing-Tao Meng
  Volume 2011 (2011), Article ID 107091, 4 pages
• Animal Models of Cardiovascular Diseases, Carlos Zaragoza, Carmen Gomez-Guerrero, Jose Luis Martin-Ventura, Luis Blanco-Colio, Begoña Lavin, Beñat Mallavia, Carlos Tarin, Sebastian Mas, Alberto Ortiz, and Jesus Egido
  Volume 2011 (2011), Article ID 497841, 13 pages
• The Representative Porcine Model for Human Cardiovascular Disease, Yoriyasu Suzuki, Alan C. Yeung, and Fumiaki Ikeno
  Volume 2011 (2011), Article ID 195483, 10 pages
• Genetically Modified Mouse Models Used for Studying the Role of the AT₂ Receptor in Cardiac Hypertrophy and Heart Failure, Maria D. Avila, James P. Morgan, and Xinhua Yan
  Volume 2011 (2011), Article ID 141039, 5 pages
• Aortocaval Fistula in Rat: A Unique Model of Volume-Overload Congestive Heart Failure and Cardiac Hypertrophy, Zaid Abassi, Ilia Goltsman, Tony Karram, Joseph Winaver, and Aaron Hoffman
  Volume 2011 (2011), Article ID 729497, 13 pages
• Bovine Model of Doxorubicin-Induced Cardiomyopathy, Carlo R. Bartoli, Kenneth R. Brittian, Guruprasad A. Giridharan, Steven C. Koenig, Tariq Hamid, and Sumanth D. Prabhu
  Volume 2011 (2011), Article ID 758736, 11 pages
• Comparison of Myocardial Remodeling between Cryoinfarction and Reperfused Infarction in Mice, Georg D. Duerr, Naziha Elhafi, Toktam Bostani, Joerg Ellinger, Louay Swieny, Elvis Kolobara, Armin Welz, and Oliver Dewald
  Volume 2011 (2011), Article ID 961298, 10 pages
• Cardiac Imaging Using Clinical 1.5 T MRI Scanners in a Murine Ischemia/Reperfusion Model, Jakob G. J. Voelkl, Bernhard J. Haubner, Christian Kremser, Agnes Mayr, Gert Klug, Alexander Loizides, Silvana Müller, Otmar Pachinger, Michael Schocke, and Bernhard Metzler
  Volume 2011 (2011), Article ID 185683, 8 pages
• Assessment of Elastase-Induced Murine Abdominal Aortic Aneurysms: Comparison of Ultrasound Imaging with In Situ Video Microscopy, Junya Azuma, Lars Maegdefessel, Toshiro Kitagawa, Ronald L. Dalman, Michael V. McConnell, and Philip S. Tsao
  Volume 2011 (2011), Article ID 252141, 10 pages
• Roles of the WHHL Rabbit in Translational Research on Hypercholesterolemia and Cardiovascular Diseases, Tsutomu Kobayashi, Takashi Ito, and Masashi Shiomi
  Volume 2011 (2011), Article ID 406473, 10 pages
• Effects of Clofibrate on Salt Loading-Induced Hypertension in Rats, Antonio Cruz, Isabel Rodríguez-Gómez, Rocío Pérez-Abud, Miguel Ángel Vargas, Rosemary Wangensteen, Andrés Quesada, Antonio Osuna, and Juan Manuel Moreno
  Volume 2011 (2011), Article ID 469481, 8 pages
• Shen-Fu Injection Preconditioning Inhibits Myocardial Ischemia-Reperfusion Injury in Diabetic Rats: Activation of eNOS via the PI3K/Akt Pathway, Yang Wu, Zhong-yuan Xia, Qing-tao Meng, Jie Zhu, Shaoqing Lei, Jinjin Xu, and Juan Dou
  Volume 2011 (2011), Article ID 384627, 9 pages
• Placental Leucine Aminopeptidase- and Aminopeptidase A- Deficient Mice Offer Insight concerning the Mechanisms Underlying Preterm Labor and Preeclampsia, Shigehiko Mizutani, John W. Wright, and Hiroshi Kobayashi
  Volume 2011 (2011), Article ID 286947, 12 pages
• A Rabbit Model of Thrombosis on Atherosclerotic Lesions, Atsushi Yamashita and Yujiro Asada
  Volume 2011 (2011), Article ID 424929, 15 pages
• The Fat-Fed Apolipoprotein E Knockout Mouse Brachiocephalic Artery in the Study of Atherosclerotic Plaque Rupture, Andrew R. Bond and Christopher L. Jackson
  Volume 2011 (2011), Article ID 379069, 10 pages
• Atherosclerosis and Thrombosis: Insights from Large Animal Models, Gemma Vilahur, Teresa Padro, and Lina Badimon
  Volume 2011 (2011), Article ID 907575, 12 pages
• Rodent Models for Metabolic Syndrome Research, Sunil K. Panchal and Lindsay Brown
  Volume 2011 (2011), Article ID 351982, 14 pages
• Glycogen Storage Disease Type Ia in Canines: A Model for Human Metabolic and Genetic Liver Disease, Andrew Specht, Laurie Fiske, Kirsten Erger, Travis Cossette, John Verstegen, Martha Campbell-Thompson, Maggie B. Struck, Young Mok Lee, Janice Y. Chou, Barry J. Byrne, Catherine E. Correia, Cathryn S. Mah, David A. Weinstein, and Thomas J. Conlon
  Volume 2011 (2011), Article ID 646257, 9 pages
• Biology of Obesity: Lessons from Animal Models of Obesity, Keizo Kanasaki and Daisuke Koya
  Volume 2011 (2011), Article ID 197636, 11 pages
• The Effects of Erythropoietin Dose Titration during High-Fat Diet-Induced Obesity, Amanda Foskett, Mawadda Alnaeeli, Li Wang, Ruifeng Teng, and Constance T. Noguchi
  Volume 2011 (2011), Article ID 373781, 8 pages
• Long-Term Type 1 Diabetes Enhances In-Stent Restenosis after Aortic Stenting in Diabetes-Prone BB Rats, Geanina Onuta, Hendrik C. Groenewegen, Flip A. Klatter, Mark Walther Boer, Maaike Goris, Harry van Goor, Anton J. M. Roks, Jan Rozing, Bart J. G. L. de Smet, and Jan-Luuk Hillebrands
  Volume 2011 (2011), Article ID 396734, 8 pages
• Glucose Tolerance and Left Ventricular Pressure-Volume Relationships in Frequently Used Mouse Strains, Wouter Oosterlinck, Annelies Vanderper, Willem Flameng, and Paul Herijgers
  Volume 2011 (2011), Article ID 281312, 7 pages
• Animal Models to Study the Role of Long-Term Hypergastrinemia in Gastric Carcinogenesis, Reidar Fossmark, Gunnar Qvigstad, Tom Chr. Martinsen, ⌀yvind Hauso, and Helge L. Waldum
  Volume 2011 (2011), Article ID 975479, 6 pages
• Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children, Chiaming Fan, Kristen R. Georgiou, Tristan J. King, and Cory J. Xian
  Volume 2011 (2011), Article ID 903097, 8 pages
• Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer, Alessandra Drusco, Yuri Pekarsky, Stefan Costinean, Anna Antenucci, Laura Conti, Stefano Volinia, Rami I. Aqeilan, Kay Huebner, and Nicola Zanesi
  Volume 2011 (2011), Article ID 984505, 10 pages
• Morphological and Molecular Alterations in 1,2 Dimethylhydrazine and Azoxymethane Induced Colon Carcinogenesis in Rats, Martina Perše and Anton Cerar
  Volume 2011 (2011), Article ID 473964, 14 pages
• Vanadium Inhalation in a Mouse Model for the Understanding of Air-Suspended Particle Systemic Repercussion, T. I. Fortoul, V. Rodriguez-Lara, A. Gonzalez-Villalva, M. Rojas-Lemus, G. Cano-Gutierrez, M. Ustarroz-Cano, L. Colin-Barenque, L. F. Montaño, I. García-Pelez, P. Bizarro-Nevares, N. Lopez-Valdez, C. I. Falcon-Rodriguez, R. S. Jimenez-Martínez, M. L. Ruiz-Guerrero, L. S. López-Zepeda, A. Morales-Rivero, and A. Muñiz-Rivera-Cambas
  Volume 2011 (2011), Article ID 951043, 11 pages
• Animal Models of Middle Ear Cholesteatoma, Tomomi Yamamoto-Fukuda, Haruo Takahashi, and Takehiko Koji
  Volume 2011 (2011), Article ID 394241, 11 pages
• Rabbit Model of Retinoblastoma, Shin Jeong Kang and Hans E. Grossniklaus
  Volume 2011 (2011), Article ID 394730, 5 pages
• Animal Models of Colitis-Associated Carcinogenesis, Manasa Kanneganti, Mari Mino-Kenudson, and Emiko Mizoguchi
  Volume 2011 (2011), Article ID 342637, 23 pages
• Anti-VEGF Therapy in Breast and Lung Mouse Models of Cancers, Di Domenico Marina, Ricciardi Carmela, Fusco Alfredo, and Pierantoni Giovanna Maria
  Volume 2011 (2011), Article ID 947928, 4 pages
• Mouse Models of Escherichia coli O157:H7 Infection and Shiga Toxin Injection, Krystle L. Mohawk and Alison D. O'Brien
  Volume 2011 (2011), Article ID 258185, 17 pages
• Animal Models of Bacterial Keratitis, Mary E. Marquart
  Volume 2011 (2011), Article ID 680642, 12 pages
• Laboratory Animal Models for Brucellosis Research, Teane M. A. Silva, Erica A. Costa, Tatiane A. Paixão, Renée M. Tsolis, and Renato L. Santos
  Volume 2011 (2011), Article ID 518323, 9 pages
• Bronchiolitis Obliterans Organizing Pneumonia in Swine Associated with Porcine Circovirus Type 2 Infection, Ching-Chang Cheng, Yen-Feng Lee, Nai-Nu Lin, Chieh-Liang Wu, Kwong-Chung Tung, and Yung-Tsung Chiu
  Volume 2011 (2011), Article ID 245728, 9 pages
• Effects of a Tumor Necrosis Factor-α Antagonist on Experimentally Induced Rhinosinusitis, Dong-Hyun Kim, Eun-ju Jeon, Shi-Nae Park, Kyung-Ho Park, Yong-Soo Park, and Sang Won Yeo
  Volume 2011 (2011), Article ID 360457, 9 pages