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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 197636, 11 pages
http://dx.doi.org/10.1155/2011/197636
Review Article

Biology of Obesity: Lessons from Animal Models of Obesity

Division of Diabetes & Endocrinology, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan

Received 14 September 2010; Accepted 13 December 2010

Academic Editor: Monica Fedele

Copyright © 2011 Keizo Kanasaki and Daisuke Koya. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Naila Rabbani, and Paul J. Thornalley, “Glyoxalase in diabetes, obesity and related disorders,” Seminars in Cell & Developmental Biology, vol. 22, no. 3, pp. 309–317, 2011. View at Publisher · View at Google Scholar
  • Mónica Moreira-Rodrigues, Janete Quelhas-Santos, Roberto Roncon-Albuquerque, Paula Serrão, Adelino Leite-Moreira, Benedita Sampaio-Maia, and Manuel Pestana, “Blunted renal dopaminergic system in a mouse model of diet-induced obesity,” Experimental Biology and Medicine, vol. 237, no. 8, pp. 949–955, 2012. View at Publisher · View at Google Scholar
  • M. R. Bonsignore, W. T. McNicholas, J. M. Montserrat, and J. Eckel, “Adipose tissue in obesity and obstructive sleep apnoea,” European Respiratory Journal, vol. 39, no. 3, pp. 746–767, 2012. View at Publisher · View at Google Scholar
  • Sharma Prabhakar, “Translational research challenges: Finding the right animal models,” Journal of Investigative Medicine, vol. 60, no. 8, pp. 1141–1146, 2012. View at Publisher · View at Google Scholar
  • Isaac Almendros, Josep M. Montserrat, Marta Torres, Maria R. Bonsignore, Laura Chimenti, Daniel Navajas, and Ramon Farré, “Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea,” Sleep Medicine, vol. 13, no. 10, pp. 1254–1260, 2012. View at Publisher · View at Google Scholar
  • Peter A. Hecker, M. Faadiel Essop, William C. Stanley, Rudo F. Mapanga, Charlene P. Kimar, Rogerio F. Ribeiro, Bethany H. Brown, Kelly A. O'Connell, James W. Cox, Kadambari C. Shekar, and Girma Asemu, “Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets,” American Journal of Physiology - Endocrinology and Metabolism, vol. 303, no. 8, pp. E959–E972, 2012. View at Publisher · View at Google Scholar
  • Ana Butorac, Martina Basic, and Irena Landeka Jurcevic, “Obesity: Genome And Environment Interactions,” Arhiv Za Higijenu Rada I Toksikologiju, vol. 63, no. 3, pp. 395–405, 2012. View at Publisher · View at Google Scholar
  • Rodrigo Mello Gomes, Angélica Sbrolini Marques, Rosana Torrezan, Dionizia Xavier Scomparin, Paulo Cezar De Freitas Mathias, and Wilson Rinaldi, “Effect of moderate exercise program on rats from different models of obesity,” Revista da Educacao Fisica, vol. 23, no. 2, pp. 285–294, 2012. View at Publisher · View at Google Scholar
  • Ruozhi Zhao, Khuong Le, Mohammed H. Moghadasian, and Garry X. Shen, “Regulatory role of NADPH oxidase in glycated LDL-induced upregulation of plasminogen activator inhibitor-1 and heat shock factor-1 in mouse embryo fibroblasts and diabetic mice,” Free Radical Biology and Medicine, vol. 61, pp. 18–25, 2013. View at Publisher · View at Google Scholar
  • H. S. Abed, and G. A. Wittert, “Obesity and atrial fibrillation,” Obesity Reviews, 2013. View at Publisher · View at Google Scholar
  • Shogo Ikeda, Shigeri Maruyama, Seiji Shioyama, Mayumi Kikuchi, Ayako Kawaguchi, Tetsuo Yamada, and Takuya Ikeda, “Development of an Efficient Genotyping Method to Detect Obese Mutation in t he Mouse Leptin Gene for Use in SPF Barrier Facilities,” Journal of Veterinary Medical Science, vol. 75, no. 5, pp. 633–638, 2013. View at Publisher · View at Google Scholar
  • Yan Ping Zhang, Chun Yu Song, Yue Yuan, Ariel Eber, Yiliam Rodriguez, Roy C. Levitt, Peter Takacs, Zhe Yang, Ronald Goldberg, and Keith A. Candiotti, “Diabetic neuropathic pain development in type 2 diabetic mouse model and the prophylactic and therapeutic effects of coenzyme Q10,” Neurobiology of Disease, 2013. View at Publisher · View at Google Scholar
  • Ling Xu, Megumi Kanasaki, Jianhua He, Munehiro Kitada, Kenji Nagao, Hiroko Jinzu, Yasushi Noguchi, Hiroshi Maegawa, Keizo Kanasaki, and Daisuke Koya, “Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules,” Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2013. View at Publisher · View at Google Scholar
  • William R. Scott, Rachel L. Batterham, Cigdem Gelegen, Keval Chandarana, Efthimia Karra, Ahmed Yousseif, Chloé Amouyal, Agharul I. Choudhury, Fabrizio Andreelli, and Dominic J. Withers, “Differential Pre-mRNA Splicing Regulates Nnat Isoforms in the Hypothalamus after Gastric Bypass Surgery in Mice,” PLoS ONE, vol. 8, no. 3, 2013. View at Publisher · View at Google Scholar
  • I. Scroyen, B. Hemmeryckx, and H. R. Lijnen, “From mice to men: mouse models in obesity research: What can we learn?,” Thrombosis and Haemostasis, vol. 109, no. 5, 2013. View at Publisher · View at Google Scholar
  • Ulla Renne, Martina Langhammer, Julia Brenmoehl, Christina Walz, Anja Zeissler, Armin Tuchscherer, Marion Piechotta, Rudolf J. Wiesner, and Maximilian Bielohuby, “Lifelong Obesity in a Polygenic Mouse Model Prevents Age- and Diet-Induced Glucose Intolerance- Obesity Is No Road to Late-Onset Diabetes in Mice,” Plos One, vol. 8, no. 11, 2013. View at Publisher · View at Google Scholar
  • Keizo Kanasaki, Munehiro Kitada, and Megumi Kanasaki, “The biological consequence of obesity on the kidney,” Nephrology Dialysis Transplantation, vol. 28, pp. 1–7, 2013. View at Publisher · View at Google Scholar
  • Sajid Khan, Samriddhi Shukla, Sonam Sinha, and Syed Musthapa Meeran, “Role of adipokines and cytokines in obesity-associated breast cancer: Therapeutic targets,” Cytokine & Growth Factor Reviews, 2013. View at Publisher · View at Google Scholar
  • Yang-wei Wang, Guang-dong Sun, Jing Sun, Shu-jun Liu, Ji Wang, Xiao-hong Xu, and Li-ning Miao, “Spontaneous Type 2 Diabetic Rodent Models,” Journal of Diabetes Research, vol. 2013, pp. 1–8, 2013. View at Publisher · View at Google Scholar
  • Javier Cubero, Lourdes Franco, Monica Mesa, Carmen Galan, Ana Beatriz Rodriguez, Carlos Jarne, and Carmen Barriga, “Body weight gain in rats by a high-fat diet produces chronodisruption in ac tivity/inactivity circadian rhythm,” Chronobiology International, vol. 31, no. 3, pp. 363–370, 2014. View at Publisher · View at Google Scholar