Etiological Analysis of Neurodevelopmental Disabilities: Single-Center Eight-Year Clinical Experience in South China
Figure 6
Muscular ultrastructure and brain MRI findings in a patient with congenital muscular dystrophy. In Figure 6(a), the myofibril Z lines in a muscle cell were ruptured , and the filaments between Z lines were arranged disorderly . Figure 6(b) showed the fatty degeneration of myofibrils in a muscle cell with completely vanished sarcolemma, and large quantity of collagenous fibers (ā) were observed in the endomysium (m). Figures 6(c) and 6(d) were cranial MRI findings revealing the reduced signal intensity in T1WI while increased one in T2WI, respectively, in bilateral frontal and parietal lobes, both indicating leukodystrophy.
