Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin

Figure 4

Circular dichroism spectra of WT and mutant recombinant tropomyosins in solution. Each spectrum is the average of 2-3 independent determinations. Estimates of structural content are given in Table 2. Note that curves for α-GS-Tm WT and β-GS-Tm WT overlap over most of the wavelength range.