- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 457079, 10 pages
Kainic Acid-Induced Neurodegenerative Model: Potentials and Limitations
1Department of Neurosurgery, The First Hospital of Jilin University, Changchun 130021, China
2Department of Neurobiology, Care Science and Society, Karolinska Institute, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden
3Department of Neurology, the First Hospital of Jilin University, Changchun 130021, China
Received 14 September 2010; Accepted 25 October 2010
Academic Editor: Monica Fedele
Copyright © 2011 Xiang-Yu Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [42 citations]
The following is the list of published articles that have cited the current article.
- Maria Concetta Geloso, Valentina Corvino, and Fabrizio Michetti, “Trimethyltin-induced hippocampal degeneration as a tool to investigate neurodegenerative processes,” Neurochemistry International, vol. 58, no. 7, pp. 729–738, 2011.
- Francine Deprez, Michela Zattoni, Maria Luisa Mura, Karl Frei, and Jean-Marc Fritschy, “Adoptive transfer of T lymphocytes in immunodeficient mice influences epileptogenesis and neurodegeneration in a model of temporal lobe epilepsy,” Neurobiology of Disease, vol. 44, no. 2, pp. 174–184, 2011.
- O. Y. Glushakova, A. Jeromin, J. Martinez, D. Johnson, N. Denslow, J. Streeter, R. L. Hayes, and S. Mondello, “Cerebrospinal Fluid Protein Biomarker Panel for Assessment of Neurotoxicity Induced by Kainic Acid in Rats,” Toxicological Sciences, vol. 130, no. 1, pp. 158–167, 2012.
- Dhanisha J. Jhaveri, Chanel J. Taylor, and Perry F. Bartlett, “Activation of different neural precursor populations in the adult hippocampus: Does this lead to new neurons with discrete functions?,” Developmental Neurobiology, vol. 72, no. 7, pp. 1044–1058, 2012.
- Casey M. O'Dell, Arabinda Das, Gerald Wallace, Swapan K. Ray, and Naren L. Banik, “Understanding the basic mechanisms underlying seizures in mesial temporal lobe epilepsy and possible therapeutic targets: A review,” Journal of Neuroscience Research, vol. 90, no. 5, pp. 913–924, 2012.
- Waldemar Szaroma, K. Dziubek, A. Greń, B. Kreczmer, and E. Kapusta, “Influence of the kainic acid on antioxidant status in the brain, liver and kidneys of the mouse,” Acta Physiologica Hungarica, vol. 99, no. 4, pp. 447–459, 2012.
- J. Rowles, and M. Olsen, “Perspectives on the development of antioxidant antiepileptogenic agents,” Mini-Reviews in Medicinal Chemistry, vol. 12, no. 10, pp. 1015–1027, 2012.
- Mitsumasa Fukuda, Hitomi Hino, Yuka Suzuki, Hisaaki Takahashi, Takehiko Morimoto, and Eiichi Ishii, “Postnatal interleukin-1β enhances adulthood seizure susceptibility and neuronal cell death after prolonged experimental febrile seizures in infantile rats,” Acta Neurologica Belgica, 2013.
- Jisoo Park, Kisang Kwon, Seon-Hwan Kim, Min-Hee Yi, Enji Zhang, Gyeyeong Kong, Dong Woon Kim, and Jongsun Park, “Astrocytic phosphorylation of PDK1 on Tyr9 following an excitotoxic lesion in the mouse hippocampus,” Brain Research, 2013.
- Denise Harhausen, Andreas Wunder, Violetta Sudmann, Uldus Khojasteh, Jochen Müller, Marietta Zille, Keith Graham, Andrea Thiele, Thomas Dyrks, and Ulrich Dirnagl, “Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke,” PLoS ONE, vol. 8, no. 8, 2013.
- Rajeev Shrestha, Owain Millington, James Brewer, Kumlesh K. Dev, and Trevor J. Bushell, “Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways,” Neuropharmacology, 2013.
- Guodong Xiao, Weidong Hu, and Xuesong Chen, “Magnesium Lithospermate B Protects Neurons from N-Methyl-d-Aspartic Acid Injury and Attenuates Kainic Acid-Induced Neurodegeration in FVB Mice,” Journal of Molecular Neuroscience, 2013.
- Naredla Kesava Reddy, and Srivari Chandrasekhar, “Total Synthesis of (-)-alpha-Kainic acid via Chirality Transfer through Ireland-Claisen Rearrangement,” Journal of Organic Chemistry, vol. 78, no. 7, pp. 3355–3360, 2013.
- Ricardo Marques, Cláudio J. Maia, Cátia Vaz, Sara Correia, and Sílvia Socorro, “The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease,” Cellular and Molecular Life Sciences, 2013.
- V. Corvino, E. Marchese, F. Michetti, and M.C. Geloso, “Neuroprotective strategies in hippocampal neurodegeneration induced by the neurotoxicant trimethyltin,” Neurochemical Research, vol. 38, no. 2, pp. 240–253, 2013.
- David Gosselin, Marc-André Bellavance, and Serge Rivest, “IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults,” Frontiers in Cellular Neuroscience, 2013.
- Rubén Darío Castro-Torres, Verónica Chaparro-Huerta, Mario Eduardo Flores-Soto, Jacinto Bañuelos-Pineda, Antoni Camins, Sandra A. Orozco-Suárez, Juan Armendáriz-Borunda, and Carlos Beas-Zárate, “A Single Dose of Pirfenidone Attenuates Neuronal Loss and Reduces Lipid Peroxidation after Kainic Acid-Induced Excitotoxicity in the Pubescent Rat Hippocampus,” Journal of Molecular Neuroscience, 2013.
- Stefan Plantman, “Proregenerative Properties of ECM Molecules,” BioMed Research International, vol. 2013, pp. 1–11, 2013.
- Kenneth L. Pitter, Ilaria Tamagno, Xi Feng, Kaushik Ghosal, Nduka Amankulor, Eric C. Holland, and Dolores Hambardzumyan, “The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions,” Glia, 2014.
- Kangning Xu, Yufen Zhang, Yan Wang, Peng Ling, Xin Xie, Chenyao Jiang, Zhizhen Zhang, and Xiao-Yuan Lian, “Ginseng Rb Fraction Protects Glia, Neurons and Cognitive Function in a Rat Model of Neurodegeneration,” Plos One, vol. 9, no. 6, 2014.
- Karen Tse, Sreekanth Puttachary, Edward Beamer, Graeme J. Sills, and Thimmasettappa Thippeswamy, “Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies,” Plos One, vol. 9, no. 5, 2014.
- Kentaro Oe, and Yasufumi Ohfune, “Short Total Synthesis of (-)-Kainic Acid,” Organic Letters, vol. 16, no. 9, pp. 2550–2553, 2014.
- Irene Bolea, Maria Alessandra Colivicchi, Chiara Ballini, José Marco-Contelles, Keith Francis Tipton, Mercedes Unzeta, and Laura Della Corte, “ Neuroprotective Effects of the MAO-B Inhibitor, PF9601N, in an In Vivo Model of Excitotoxicity ,” CNS Neuroscience & Therapeutics, 2014.
- István Koncz, Bernadett K. Szász, Szilárd I. Szabó, János P. Kiss, Árpád Mike, Balázs Lendvai, E. Sylvester Vizi, and Tibor Zelles, “The tricyclic antidepressant desipramine inhibited the neurotoxic, kainate-induced [Ca2+]i increases in CA1 pyramidal cells in acute hippocampal slices,” Brain Research Bulletin, 2014.
- Werner Hoppenstedt, “PID in der Reproduktionsmedizin,” Biologie in unserer Zeit, vol. 44, no. 5, pp. 328–335, 2014.
- Mummedy Swamy, Dian Suhaili, K. N. . S. Sirajudeen, Zulkarnain Mustapha, and Chandran Govindasamy, “PROPOLIS AMELIORATES TUMOR NEROSIS FACTOR-alpha, NITRIC OXIDE LEVELS, CASPASE-3 AND NITRIC OXIDE SYNTHASE ACTIVITIES IN KAINIC ACID MEDIATED EXCITOTOXICITY IN RAT BRAIN,” African Journal of Traditional Complementary and Alternative Medicines, vol. 11, no. 5, pp. 48–53, 2014.
- Chia Ying Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Shang Shing Peter Chou, and Su Jane Wang, “Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats,” NeuroToxicology, 2015.
- Natalia Lobanovskaya, Tamara Zharkovsky, Külli Jaako, Monika Jürgenson, Anu Aonurm-Helm, and Alexander Zharkovsky, “PSA modification of NCAM supports the survival of injured retinal ganglion cells in adulthood,” Brain Research, 2015.
- Sreekanth Puttachary, Shaunik Sharma, Karen Tse, Edward Beamer, Abby Sexton, Joseph Crutison, and Thimmasettappa Thippeswamy, “Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry,” Plos One, vol. 10, no. 7, 2015.
- Christian Jaeger, Enrico Glaab, Alessandro Michelucci, Tina M. Binz, Sandra Koeglsberger, Pierre Garcia, Jean-Pierre Trezzi, Jenny Ghelfi, Rudi Balling, and Manuel Buttini, “The Mouse Brain Metabolome,” The American Journal of Pathology, 2015.
- Letteria Minutoli, Herbert Marini, Mariagrazia Rinaldi, Alessandra Bitto, Natasha Irrera, Gabriele Pizzino, Francesco Squadrito, Domenica Altavilla, Giovanni Pallio, Margherita Calò, Elena Bianca Adamo, Vincenzo Trichilo, Monica Interdonato, and Federica Galfo, “A Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase Protects Against Kainic Acid-Induced Brain Injury,” NeuroMolecular Medicine, vol. 17, no. 2, pp. 192–201, 2015.
- Navjot Shah, Rumani Singh, Upasana Sarangi, Nishant Saxena, Anupama Chaudhary, Gurcharan Kaur, Sunil C. Kaul, and Renu Wadhwa, “Combinations of Ashwagandha Leaf Extracts Protect Brain-Derived Cells against Oxidative Stress and Induce Differentiation,” Plos One, vol. 10, no. 3, 2015.
- Rubén Darío Castro-Torres, Verónica Chaparro-Huerta, Mario Eduardo Flores-Soto, Luis Jave-Suárez, Antoni Camins, Juan Armendáriz-Borunda, Carlos Beas-Zárate, and Salvador Mena-Munguía, “Pirfenidone Attenuates Microglial Reactivity and Reduces Inducible Nitric Oxide Synthase mRNA Expression After Kainic Acid-Mediated Excitotoxicity in Pubescent Rat Hippocampus,” Journal of Molecular Neuroscience, 2015.
- Dai Kezuka, Mika Tkarada-Iemata, Tsuyoshi Hattori, Kazutoshi Mori, Ryosuke Takahashi, Yasuko Kitao, and Osamu Hori, “Deletion of Atf6α enhances kainate-induced neuronal death in mice,” Neurochemistry International, 2015.
- Christopher Shamir, Chaitra Venugopal, and Anandh Dhanushkodi, “Dental pulp stem cells for treating neurodegenerative diseases,” Neural Regeneration Research, vol. 10, no. 12, pp. 1910–1911, 2015.
- Angie Ambers, Meredith Turnbough, Robert Benjamin, Harrell Gill-King, Jonathan King, Antti Sajantila, and Bruce Budowle, “Modified DOP-PCR for Improved STR Typing of Degraded DNA from Human Skeletal Remains and Bloodstains,” Legal Medicine, 2015.
- Kyoung Hoon Jeong, Un Ju Jung, and Sang Ryong Kim, “ Naringin Attenuates Autophagic Stress and Neuroinflammation in Kainic Acid-Treated Hippocampus In Vivo ,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, pp. 1–9, 2015.
- Nur Shafika Mohd Sairazi, K. N. S. Sirajudeen, Mohd Asnizam Asari, Mustapha Muzaimi, Swamy Mummedy, and Siti Amrah Sulaiman, “Kainic Acid-Induced Excitotoxicity Experimental Model: Protective Merits of Natural Products and Plant Extracts,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, pp. 1–15, 2015.
- Ouafa Najyb, Sonia Do Carmo, Azadeh Alikashani, and Eric Rassart, “Apolipoprotein D Overexpression Protects Against Kainate-Induced Neurotoxicity in Mice,” Molecular Neurobiology, 2016.
- Fengling Li, and Lei Liu, “SIRT5 Deficiency Enhances Susceptibility to Kainate-Induced Seizures and Exacerbates Hippocampal Neurodegeneration not through Mitochondrial Antioxidant Enzyme SOD2,” Frontiers in Cellular Neuroscience, vol. 10, 2016.
- Tzu Yu Lin, Cheng Wei Lu, and Su Jane Wang, “Luteolin protects the hippocampus against neuron impairments induced by kainic acid in rats,” NeuroToxicology, 2016.
- Julio Reyes-Mendoza, and Teresa Morales, “Post-treatment with prolactin protects hippocampal CA1 neurons of the ovariectomized female rat against kainic acid-induced neurodegeneration,” Neuroscience, 2016.