Review Article

Studies of Complex Biological Systems with Applications to Molecular Medicine: The Need to Integrate Transcriptomic and Proteomic Approaches

Figure 2

Integrated overview of the main ageing/T3-induced transcriptomic and proteomic alterations occurring in mammalian skeletal muscle. Schematic representation of the common events and mechanisms underlying the response of skeletal muscle to either ageing or T3 according to data obtained from cDNA microarray/proteomic-based studies in various mammalian models of ageing and thyroid state (mouse, rat, and human) (for details, see text and Tables 1, 2, 3, and 4).
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