Research Article

Simultaneous Quantification of Mitochondrial DNA Damage and Copy Number in Circulating Blood: A Sensitive Approach to Systemic Oxidative Stress

Figure 5

Ex vivo mtDNA damage response to exogenous H2O2 whole blood. Blood from six healthy male volunteers were collected and stored at −80°C. Blood cells from the whole blood samples were separated into three groups in the same manner as lymphocyte samples in Figure 4. (a) Total mtDNA content of whole blood. (b) MtDNA damage response of whole blood. (* ).
157547.fig.005a
(a)
157547.fig.005b
(b)