About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 329058, 9 pages
http://dx.doi.org/10.1155/2013/329058
Research Article

1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis

1School of Medical Science and Technology, Indian Institute of Technology, Kharagpur 721302, India
2National Facility for High-Field NMR, Tata Institute of Fundamental Research, Mumbai 400005, India
3Institute of Reproductive Medicine, Kolkata 700106, India

Received 28 April 2013; Accepted 3 July 2013

Academic Editor: Nikhat J. Siddiqi

Copyright © 2013 Saikat K. Jana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Mittal, “Endometriosis-clinical perspectives,” in Proceedings of the INDO—US Workshop on Microarray in Endometriosis: Clinics to Research Laboratory, All India Institute of Medical Sciences, New Delhi, India, 2009.
  2. L. C. Giudice and L. C. Kao, “Endometriosis,” The Lancet, vol. 364, no. 9447, pp. 1789–1799, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Dutta, M. Joshi, S. Srivastava, I. Lodh, B. Chakravarty, and K. Chaudhury, “A metabonomics approach as a means for identification of potential biomarkers for early diagnosis of endometriosis,” Molecular BioSystems, vol. 8, pp. 3281–3287, 2012.
  4. K. Arumugam and Y. C. Y. Dip, “Endometriosis and infertility: the role of exogenous lipid peroxides in the peritoneal fluid,” Fertility and Sterility, vol. 63, no. 1, pp. 198–199, 1995. View at Scopus
  5. H.-N. Ho, M.-Y. Wu, S.-U. Chen, K.-H. Chao, C.-D. Chen, and Y.-S. Yang, “Total antioxidant status and nitric oxide do not increase in peritoneal fluids from women with endometriosis,” Human Reproduction, vol. 12, no. 12, pp. 2810–2815, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Wang, J. Goldberg, R. K. Sharma, A. Agarwal, and T. Falcone, “Importance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility,” Fertility and Sterility, vol. 68, no. 5, pp. 826–830, 1997. View at Publisher · View at Google Scholar · View at Scopus
  7. A. A. Murphy, N. Santanam, and S. Parthasarathy, “Endometriosis: a disease of oxidative stress?” Seminars in Reproductive Endocrinology, vol. 16, no. 4, pp. 263–273, 1998. View at Scopus
  8. A. Agarwal, A. Aponte-Mellado, B. J. Premkumar, A. Shaman, and S. Gupta, “The effects of oxidative stress on female reproduction: a review,” Reproductive Biology and Endocrinology, vol. 10, article 49, 2012.
  9. M. Szczepańska, J. Koźlik, J. Skrzypczak, and M. Mikołajczyk, “Oxidative stress may be a piece in the endometriosis puzzle,” Fertility and Sterility, vol. 79, pp. 1288–1293, 2003.
  10. L. F. Carvalho, A. N. Samadder, A. Agarwal, L. F. Fernandes, and M. S. Abrão, “Oxidative stress biomarkers in patients with endometriosis: systematic review,” Archives of Gynecology and Obstetrics, vol. 286, pp. 1033–1040, 2012.
  11. O. Beckonert, H. C. Keun, T. M. D. Ebbels et al., “Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts,” Nature protocols, vol. 2, no. 11, pp. 2692–2703, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. W. S. Price, “Applications of pulsed gradient spin-echo NMR diffusion measurements to solution dynamics and organization,” in Diffusion Fundamentals, J. Karger, F. Grinberg, and P. Heitjans, Eds., pp. 490–508, Leipzig University Press, Leipzig, Germany, 2005.
  13. J. Liu, L. Litt, M. R. Segal, M. J. S. Kelly, J. G. Pelton, and M. Kim, “Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites,” International Journal of Molecular Sciences, vol. 12, no. 10, pp. 6469–6501, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Chaudhury, K. N. Babu, A. K. Singh, S. Das, A. Kumar, and S. Seal, “Mitigation of endometriosis using regenerative cerium oxide nanoparticles,” Nanomedicine, vol. 9, pp. 439–448, 2012.
  15. J. A. Buege and S. D. Aust, “Microsomal lipid peroxidation,” Methods in Enzymology, vol. 52, pp. 302–310, 1978. View at Publisher · View at Google Scholar · View at Scopus
  16. I. L. C. Chapple, “Reactive oxygen species and antioxidants in inflammatory diseases,” Journal of Clinical Periodontology, vol. 24, no. 5, pp. 287–296, 1997. View at Scopus
  17. S. Marklund and G. Marklund, “Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase,” European Journal of Biochemistry, vol. 47, no. 3, pp. 469–474, 1974. View at Scopus
  18. H. Aebi, “Catalase in vitro,” Methods in Enzymology, vol. 105, pp. 121–126, 1984. View at Publisher · View at Google Scholar · View at Scopus
  19. M. S. Moron, J. W. Depierre, and B. Mannervik, “Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver,” Biochimica et Biophysica Acta, vol. 582, no. 1, pp. 67–78, 1979. View at Scopus
  20. V. Witko-Sarsat, M. Friedlander, C. Capeillere-Blandin, et al., “Advanced oxidation protein products as a novel marker of oxidative stress in uremia,” Kidney International, vol. 49, pp. 1304–1313, 1996.
  21. J. Xia, R. Mandal, I. V. Sinelnikov, D. Broadhurst, and D. S. Wishart, “MetaboAnalyst 2. 0—a comprehensive server for metabolomic data analysis,” Nucleic Acids Research, vol. 40, pp. 127–133, 2012.
  22. J. Xia and D. S. Wishart, “Chapter 14: metabolomic data processing, analysis, and interpretation using MetaboAnalyst,” in Current Protocols in Bioinformatics, 2011.
  23. J. Xia, N. Psychogios, N. Young, and D. S. Wishart, “MetaboAnalyst: a web server for metabolomic data analysis and interpretation,” Nucleic Acids Research, vol. 37, no. 2, pp. W652–W660, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Carrola, C. M. Rocha, A. S. Barros et al., “Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine,” Journal of Proteome Research, vol. 10, no. 1, pp. 221–230, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Xia and D. S. Wishart, “Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst,” Nature Protocols, vol. 6, no. 6, pp. 743–760, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. M. A. Bedaiwy, T. Falcone, R. K. Sharma et al., “Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial,” Human Reproduction, vol. 17, no. 2, pp. 426–431, 2002. View at Scopus
  27. A. Shanti, N. Santanam, A. J. Morales, S. Parthasarathy, and A. A. Murphy, “Autoantibodies to markers of oxidative stress are elevated in women with endometriosis,” Fertility and Sterility, vol. 71, no. 6, pp. 1115–1118, 1999. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Ota, S. Igarashi, J. Hatazawa, and T. Tanaka, “Immunohistochemical assessment of superoxide dismutase expression in the endometrium in endometriosis and adenomyosis,” Fertility and Sterility, vol. 72, no. 1, pp. 129–134, 1999. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Yuan, S.-X. Liu, and J.-W. Tian, “Advanced oxidation protein products induce reactive oxygen species production in endothelial cells,” Di Yi Jun Yi Da Xue Xue Bao, vol. 24, no. 12, pp. 1350–1352, 2004. View at Scopus
  30. V. Witko-Sarsat, V. Gausson, A.-T. Nguyen et al., “AOPP-induced activation of human neutrophil and monocyte oxidative metabolism: a potential target for N-acetylcysteine treatment in dialysis patients,” Kidney International, vol. 64, no. 1, pp. 82–91, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. D. M. Townsend, K. D. Tew, and H. Tapiero, “The importance of glutathione in human disease,” Biomedicine and Pharmacotherapy, vol. 57, no. 3, pp. 145–155, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Meister and M. E. Anderson, “Glutathione,” Annual Review of Biochemistry, vol. 52, pp. 711–760, 1983. View at Scopus
  33. C. Kerksick and D. Willoughby, “The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress,” Journal of the International Society of Sports Nutrition, vol. 2, pp. 38–44, 2005.
  34. J. B. Owen and D. A. Butterfield, “Measurement of oxidized/reduced glutathione ratio,” Methods in Molecular Biology, vol. 648, pp. 269–277, 2010. View at Scopus
  35. T. Soga, R. Baran, M. Suematsu et al., “Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption,” Journal of Biological Chemistry, vol. 281, no. 24, pp. 16768–16776, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. I. Milic, M. Fedorova, K. Teuber, J. Schiller, and R. Hoffmann, “Characterization of oxidation products from 1-palmitoyl-2-linoleoyl-sn- glycerophosphatidylcholine in aqueous solutions and their reactions with cysteine, histidine and lysine residues,” Chemistry and Physics of Lipids, vol. 165, no. 2, pp. 186–196, 2012. View at Publisher · View at Google Scholar · View at Scopus