Development of Microencapsulation Delivery System for Long-Term Preservation of Probiotics as Biotherapeutics Agent

Table 3

Relative pH and transit time at various locations within GIT.

Region	pH	Transit time
Oesophagus	~7.0	10–14 seconds
Stomach	1–2.5 (up to 5 fed)	Half emptying: ~80.5 mins
Proximal small intestine	6.15–7.35	3.2±1.6 hrs (combined)
Distal small intestine	6.80–7.88
Ascending colon	5.26–6.72	Highly variable, dependent on bowel evacuation
Descending colon	5.20–7.02