About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 910941, 9 pages
http://dx.doi.org/10.1155/2013/910941
Research Article

Robust Cell Size Checkpoint from Spatiotemporal Positive Feedback Loop in Fission Yeast

Jie Yan,1 Xin Ni,2 and Ling Yang1,2

1School of Mathematical Sciences, Soochow University, Suzhou 215006, China
2Center for Systems Biology, Soochow University, Suzhou 215006, China

Received 29 April 2013; Accepted 7 June 2013

Academic Editor: Tao Huang

Copyright © 2013 Jie Yan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Fantes and P. Nurse, “Control of cell size at division in fission yeast by a growth modulated size control over nuclear division,” Experimental Cell Research, vol. 107, no. 2, pp. 377–386, 1977. View at Scopus
  2. A. Sveiczer, B. Novak, and J. M. Mitchison, “The size control of fission yeast revisited,” Journal of Cell Science, vol. 109, part 12, pp. 2947–2957, 1996. View at Scopus
  3. I. Rupeš, B. A. Webb, A. Mak, and P. G. Young, “G2/M arrest caused by actin disruption is a manifestation of the cell size checkpoint in fission yeast,” Molecular Biology of the Cell, vol. 12, no. 12, pp. 3892–3903, 2001. View at Scopus
  4. Y. Masui and P. Wang, “Cell cycle transition in early embryonic development of Xenopus laevis,” Biology of the Cell, vol. 90, no. 8, pp. 537–548, 1998. View at Scopus
  5. P. Wang, S. Hayden, and Y. Masui, “Transition of the blastomere cell cycle from cell size-independent to size-dependent control at the midblastula stage in Xenopus laevis,” Journal of Experimental Zoology, vol. 287, no. 2, pp. 128–144, 2000.
  6. B. A. Edgar and C. F. Lehner, “Developmental control of cell cycle regulators: a fly's perspective,” Science, vol. 274, no. 5293, pp. 1646–1652, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Dolznig, F. Grebien, T. Sauer, H. Beug, and E. W. Müllner, “Evidence for a size-sensing mechanism in animal cells,” Nature Cell Biology, vol. 6, no. 9, pp. 899–905, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Takahashi, P. G. Bhide, T. Goto, S. Miyama, and V. S. Caviness Jr., “Proliferative behavior of the murine cerebral wall in tissue culture: cell cycle kinetics and checkpoints,” Experimental Neurology, vol. 156, no. 2, pp. 407–417, 1999. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Sveiczer, J. J. Tyson, and B. Novak, “Modelling the fission yeast cell cycle,” Briefings in Functional Genomics and Proteomics, vol. 2, no. 4, pp. 298–307, 2004. View at Scopus
  10. A. Sveiczer, A. Csikasz-Nagy, B. Gyorffy, J. J. Tyson, and B. Novak, “Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Δ mutant cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 14, pp. 7865–7870, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. B. Novak, Z. Pataki, A. Ciliberto, and J. J. Tyson, “Mathematical model of the cell division cycle of fission yeast,” Chaos, vol. 11, no. 1, pp. 277–286, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. Z. Qu, J. N. Weiss, and W. R. MacLellan, “Coordination of cell growth and cell division: a mathematical modeling study,” Journal of Cell Science, vol. 117, no. 18, pp. 4199–4207, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. J. R. Pomerening, Y. K. Sun, and J. E. Ferrell Jr., “Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations,” Cell, vol. 122, no. 4, pp. 565–578, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. S. G. Martin and M. Berthelot-Grosjean, “Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle,” Nature, vol. 459, no. 7248, pp. 852–856, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. J. B. Moseley, A. Mayeux, A. Paoletti, and P. Nurse, “A spatial gradient coordinates cell size and mitotic entry in fission yeast,” Nature, vol. 459, no. 7248, pp. 857–860, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Vilela, J. J. Morgan, and P. A. Lindahl, “Mathematical model of a cell size checkpoint,” PLoS Computational Biology, vol. 6, no. 12, Article ID e1001036, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Y. Tsai, S. C. Yoon, W. Ma, J. R. Pomerening, C. Tang, and J. E. Ferrell Jr., “Robust, tunable biological oscillations from interlinked positive and negative feedback loops,” Science, vol. 321, no. 5885, pp. 126–139, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. B. Novak and J. J. Tyson, “Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos,” Journal of Cell Science, vol. 106, part 4, pp. 1153–1168, 1993. View at Scopus
  19. J. E. Ferrell Jr., “Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability,” Current Opinion in Cell Biology, vol. 14, no. 2, pp. 140–148, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. F. R. Cross, V. Archambault, M. Miller, and M. Klovstad, “Testing a mathematical model of the yeast cell cycle,” Molecular Biology of the Cell, vol. 13, no. 1, pp. 52–70, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. P. A. Fantes, “Control of cell size and cycle time in Schizosaccharomyces pombe,” Journal of Cell Science, vol. 24, pp. 51–67, 1977. View at Scopus
  22. P. Nurse and P. Thuriaux, “Controls over the timing of DNA replication during the cell cycle of fission yeast,” Experimental Cell Research, vol. 107, no. 2, pp. 365–375, 1977. View at Scopus
  23. J. Lei, “Stochasticity in single gene expression with both intrinsic noise and fluctuation in kinetic parameters,” Journal of Theoretical Biology, vol. 256, no. 4, pp. 485–492, 2009.
  24. L. Yang, Z. Han, W. R. MacLellan, J. N. Weiss, and Z. Qu, “Linking cell division to cell growth in a spatiotemporal model of the cell cycle,” Journal of Theoretical Biology, vol. 241, no. 1, pp. 120–133, 2006.
  25. B. Novak, A. Csikasz-Nagy, B. Gyorffy, K. Chen, and J. J. Tyson, “Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions,” Biophysical Chemistry, vol. 72, no. 1-2, pp. 185–200, 1998. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Sveiczer, J. J. Tyson, and B. Novak, “A stochastic, molecular model of the fission yeast cell cycle: role of the nucleocytoplasmic ratio in cycle time regulation,” Biophysical Chemistry, vol. 92, no. 1-2, pp. 1–15, 2001. View at Publisher · View at Google Scholar · View at Scopus
  27. Z. Qu, W. R. MacLellan, and J. N. Weiss, “Dynamics of the cell cycle: checkpoints, sizers, and timers,” Biophysical Journal, vol. 85, no. 6, pp. 3600–3611, 2003. View at Scopus