Detection Progress of Selected Drugs in TLC

Table 6

Characteristics of the visualizing effect for selected phenolic compounds.

Detected drug	Stationary phase	Mobile phase	Visualizing reagent	Detection limit (µg)	Detectability index (µg/mm^2)	Color of spot	Background color of chromatogram	Reference
Adrenaline	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Brilliant cresyl blue in 5% NaOH	0.10	0.10/10	Brown	Light violet	[61]
	Silica gel 60/kieselguhr F254		Bromocresol green in 5% NaOH	0.25	0.25/47	Light brown	Sea/green
	Polyamide 11F254		Eosin yellow in 5% NaOH	2.50	2.50/30	Light brown	Light yellow
Dopamine	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Bromocresol green in 5% NaOH	0.10	0.10/15	Orange	Light blue	[61]
	Silica gel 60/kieselguhr F254			0.25	0.25/10	Brown/orange	Sea/green
	Polyamide 11F254		Eosin yellow in 5% NaOH	0.75	0.75/17	Light brown	Light yellow
Metaraminol	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Bromocresol green in 5% NaOH	0.50	0.50/15	Lemon	Light blue	[61]
	Silica gel 60/kieselguhr F254		Eriochrome black T in 5% NaOH	0.50	0.50/35	Brown	Light brown
	Polyamide 11F254		Aniline blue in water	50	50/42	Light yellow	Blue
Fenoterol	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Bromocresol green in 5% NaOH	0.10	0.10/13	Brown/orange	Light blue	[61]
	Silica gel 60/kieselguhr F254		Eriochrome black T in 5% NaOH	0.50	0.50/38	Brown	Light brown
	Polyamide 11F254		Eosin yellow in 5% NaOH	5.0	5/15	Yellow	Light yellow
Phenylephrine	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Bromocresol green in 5% NaOH	0.25	0.25/21	Lemon	Light blue	[61]
	Silica gel 60/kieselguhr F254		Eriochrome black T in 5% NaOH	0.50	0.50/41	Brown	Light brown
Bithionol	Silica gel 60F254	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Brilliant cresyl blue in 5% NaOH	0.50	0.50/77	Brown	Light violet	[61]
	Silica gel 60/kieselguhr F254		Brilliant cresyl blue in 5% NaOH	2.50	2.50/68	Brown	Light brown
Methyldopa	Silica gel 60	Glacial acetic acid + n-butanol + water (1 : 4 : 1, v/v/v)	Thymol blue in 2% NaOH	3.2	3.2/7	Brown/black	Beige	[62]
Norepinephrine			Bromothymol blue in 2% NaOH	0.6	0.6/28	Yellow/brown	Light blue
Terbutaline			Brilliant cresyl blue in 2% NaOH	2.0	2.0/17	Light brown	Light blue
Bamethane			Aniline blue in 2% NaOH	10	10/25	Blue	Light blue
Etamivan			Aniline blue in 2% NaOH	50	50/18	White/blue	Light blue
Phloroglucinol	Silica gel 60	Chloroform + methanol (9 : 1, v/v)	Brilliant cresyl blue in 2% NaOH	2.0	2.0/23	Light brown	Light blue	[62]
Pentazocine			Aniline blue in 2% NaOH	0.5	0.5/68	White	Light blue
Hexachlorophene			Thymol blue in 2% NaOH	5.0	5.0/37	Yellow/beige	Beige
Pyrocatechine			Brilliant green in 2% NaOH	0.3	0.3/17	Light orange/red	Light green
Niclosamide			Brilliant green in 2% NaOH	0.8	0.8/18	Green	Light green
Salicylanilide			Brilliant green in 2% NaOH	0.8	0.8/16	Green	Light green
Thymol			Brilliant green in 2% NaOH	2.0	2.0/42	Yellow green	Light green
Eugenol	Silica gel 60	Benzene	Bromothymol blue in 2% NaOH	5.0	5.0/37	Light yellow	Light blue	[62]