Prevalence of Past and Reactivated Viral Infections and Efficacy of Cyclosporine A as Monotherapy or in Combination in Patients with Psoriatic Arthritis—Synergy Study: A Longitudinal Observational Study

Table 5

List of adverse events.

Adverse event	Severity	Drug-related	Systemic treatment of psoriasis or psoriatic arthritis concomitant to adverse event
Increased creatinine and increased serum cholesterol	Mild	Yes, cyclosporine	Cyclosporine
Increased creatinine	Mild	Yes, cyclosporine	Cyclosporine, sulfasalazine
Gingival hyperplasia and gingival bleeding	Mild	Yes, cyclosporine	None
Tremor	Mild	Yes, cyclosporine	Cyclosporine
Burning urination	Mild	No	Cyclosporine, methotrexate, quinolones
Urethritis	Mild	No	Fans
Urethritis (Proteus mirabilis)	Mild	No	Fans
Hypertension	Moderate	Yes, cyclosporine	Etanercept, cyclosporine
Increased creatinine	Moderate	Yes, cyclosporine	Cyclosporine
Fatigue, stomatitis, gastrointestinal disorders, and vomiting	Moderate	Yes, cyclosporine	Cyclosporine
Nausea and vomiting	Moderate	Yes, cyclosporine	Cyclosporine, methotrexate
Hypertension, altered liver Function tests	Moderate	Yes, cyclosporine	Cyclosporine
Fever, sore throat, hyposmia, hypoacusia	Moderate	No	Methotrexate
Postmicturition syncope	Moderate	No	Cyclosporine
Presyncopal episode preceded by autonomic problems (sweating, dizziness, nausea) after several episodes of diarrhea (enteritis)	Moderate	No	Cyclosporine
Renal colic	Moderate	No	Cyclosporine, leflunomide
Syncopal episode	Serious	UKN	Cyclosporine, methotrexate
Outcomes of central vein occlusion	UKN	Yes, infliximab	Infliximab, methotrexate, cyclosporine