Research Article
β-Elemene Inhibits Cell Proliferation by Regulating the Expression and Activity of Topoisomerases I and IIα in Human Hepatocarcinoma HepG-2 Cells
Figure 3
The effects of β-ELE (β-Elemene) on the proliferation of human hepatocarcinoma HepG-2 cells. Figure 3 shows the effect of different doses of β-ELE on cell proliferation at different time periods. β-ELE significantly decreased the growth of HepG-2 cells compared with the control group. The IC50s were 96.13, 80.84, and 60.95 μg/mL for 24, 48, and 72 h, respectively, and the inhibitory effect was dose- and time-dependent.