A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data

Table 4

The rank of the possibility of preexisting molecules whose downregulation causes the abnormal profiles shown in Figure 6(d).

Rank	Reaction index		(STAT3N-STAT3N)	(SOCS3)
1	PP2	0.98	0.98	0.98
2	SHP2	0.087	0.078	0.13
3	Gas-GDP	0.086	0.077	0.13
4	Sos	0.086	0.076	0.12
5	Grb2	0.085	0.075	0.12
6	PP1	0.081	0.066	0.12