Research Article

An Intensified Regimen Containing Linezolid Could Improve Treatment Response in Mycobacterium abscessus Lung Disease

Table 1

Comparison of the clinical and radiographic characteristics of the patients with Mycobacterium abscessus lung disease receiving conventional and intensified regimen.

CharacteristicConventional regimen ()Intensified regimen () value

Age (yr), median (IQR)48 (39.8–55.3)39.5 (36–43.8)0.023
Sex, female29 (85.3%)15 (93.8%)0.396
Body mass index (kg/m2), median (IQR)23.95 (22.9–24.9)24.7 (24.4–25.3)0.018
Respiratory symptoms
 Cough28 (82.4%)14 (87.5%)0.647
 Sputum28 (82.4%)14 (87.5%)0.647
 Hemoptysis6 (17.6%)2 (12.5%)0.647
Unable to produce sputum5 (14.7%)2 (12.5%)0.836
Type of disease
 Nodular bronchiectatic form28 (82.4%)14 (87.5%)0.892
 Upper lobe cavitary form3 (8.8%)1 (6.3%)
 Unclassifiable variants3 (8.8%)1 (6.3%)

Culture from bronchial washing or bronchoalveolar lavage.