(Radio)Biological Optimization of External-Beam Radiotherapy
Figure 1
Illustration of the potential of TCP/NTCP-based optimization; the two arrows on the “Tumour Dose” axis indicate two different “isotoxic” prescription doses, , associated with the full and dashed NTCP curves which correspond to “large volume” and “small volume” dose coverage of the OAR. The improvement in TCP, from ≈45% to ≈90%, that would result from such a change in dose to the tumour, is also shown.
