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Discrete Dynamics in Nature and Society
Volume 2013 (2013), Article ID 927843, 13 pages
http://dx.doi.org/10.1155/2013/927843
Research Article

Facial Edema Evaluation Using Digital Image Processing

1Departamento de Ingeniería Electrónica, Instituto Tecnológico de Morelia, Avenida Tecnológico 1500, Colonia Lomas de Santiaguito, 58120 Morelia, MICH, Mexico
2Departamento de Metrología, Centro de Investigaciones en Óptica, A.C., Loma del Bosque 115, Colonia Lomas del Campestre, 37150 León, GTO, Mexico

Received 27 October 2012; Revised 30 December 2012; Accepted 30 December 2012

Academic Editor: Ricardo Femat

Copyright © 2013 A. E. Villafuerte-Nuñez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The main objective of the facial edema evaluation is providing the needed information to determine the effectiveness of the anti-inflammatory drugs in development. This paper presents a system that measures the four main variables present in facial edemas: trismus, blush (coloration), temperature, and inflammation. Measurements are obtained by using image processing and the combination of different devices such as a projector, a PC, a digital camera, a thermographic camera, and a cephalostat. Data analysis and processing are performed using MATLAB. Facial inflammation is measured by comparing three-dimensional reconstructions of inflammatory variations using the fringe projection technique. Trismus is measured by converting pixels to centimeters in a digitally obtained image of an open mouth. Blushing changes are measured by obtaining and comparing the RGB histograms from facial edema images at different times. Finally, temperature changes are measured using a thermographic camera. Some tests using controlled measurements of every variable are presented in this paper. The results allow evaluating the measurement system before its use in a real test, using the pain model approved by the US Food and Drug Administration (FDA), which consists in extracting the third molar to generate the facial edema.