Sarcandra glabra Extract Reduces the Susceptibility and Severity of Influenza in Restraint-Stressed Mice

Table 2

Effects of SGE on the morbidity rate of restraint-stressed mice postinfection.

Grouping	Morbid mice/total mice	Morbidity (%)	Mean times to sickness (day)
Normal control	0/10	0	>21.0
Virus control	8/10	80	10.5 ± 1.8^##
Model control	9/9	100	7.2 ± 0.2^##/&&
Restraint + virus
50 mg/kg ribavirin	4/10	40	15.7 ± 2.4**
250 mg/kg SGE	9/11	82	9.7 ± 1.7
500 mg/kg SGE	9/11	82	10.0 ± 1.6*

Morbidity is presented as the percent of animals that exhibit sickness symptoms to the total number of mice. Time course of morbidity of each mouse was recorded until the 21st day after viral infection. The significance of differences was from the normal control group at (^##)𝑃<0.01, from virus control group at (^&&)𝑃<0.01, and from the model group at (**)𝑃<0.01, (*)𝑃<0.05.