A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C

Figure 4

Superposition of GCase loops 1–5 in vicinity of active site. (a) Overlay of all loops, (b) detailed comparison of loop 2, and (c) detailed comparison of loop 3. Colors are the same as in Figure 3 with the addition of grey for NN-DNJ (PDB code 2V3E).

(a)

(b)

(c)