Authors Drainage catheter/ Organ of cysts’ location Number of sessions/duration of follow-up Complications/ Complete regression (CR) at one year (disappearance of the cyst, after the first session) Near-CR at one year (volume reduction rate, after the first session >85%) Partial regression at one year (volume reduction rate, after the first session 50–85%) No response at one year (volume reduction rate <50%) Saini et al. [9 ] No (aspiration, only)/none Liver One or two/up to 24 mos. — 0% 0% 0% 100% * Zerem et al. [1 ]Yes/group I: prolonged catheter drainage for 24 hours Liver One (or two in 12.5% of group I & 26.01 of group II)/24 mos. Group I: pain/16.6% Group I: 66.7% Obscure Obscure Obscure Kairaluoma et al. [58 ] Yes/ethanol Liver One or two/12 to 32 mos. Pain, fever, and nausea-vomiting/72.7% 37.5% — 62.5% — Montorsi et al. [59 ] Yes/ethanol Liver One/6 to 60 mos. Pain, fever/9.5% 71.4% (follow-up period 12–24 mos.) Obscure Obscure 28.5% Larssen et al. [60 ] Yes/ethanol Liver One/12 to 47 mos. Pain/80% 30% 40% 20% 10% * Yang et al. [61 ]Yes* /ethanol group I: 4-hour retention, group II: 2-hour retention Liver One/9 to 59 mos. Intractable pain (32.26%), symptoms and signs of drunkenness (80.6%), flushing and headache (54%), skin rash (9.6%), deep sleep (6.4%), and blood pressure of 30–50 mm Hg (22.56%). 16.12% Obscure Obscure Obscure Zerem et al. [62 ] Yes. Two groups: continuous 24-hour catheter evacuation (I) and drainage for two hours (II)/ethanol Kidney One/24 mos. Pain/44.3% [moderate in 26.09% of cases, severe in 17.4%] 40% (at 24-month follow-up, 52% of continuous group I and 28% of group II) Obscure Obscure 7.06% Touloupidis et al. [30 ] Yes, continuous drainage of the cyst for 24 h/ethanol, retention for 20 min Kidney One or multiple (in most of cases)/5 years Pain/obscure, purulence of the cyst that required open surgery/0.4% 0 7.0% 22.0% Obscure Lin et al. [63 ] Yes/ethanol group I: 4-hour retention, group II: 2-hour retention Kidney One/12 mos. (at least) Pain (most mild to moderate, severe 13.9%), nausea, causalgia, drunkenness, perforation to the collecting system (2.7%) Group I: 21.4%, group II: 52.4% 65.7% 2.8% 0
Akinci et al. [47 ] Yes/ethanol Kidney One/12 to 85 mos. Retroperitoneal hematoma, spontaneous hemorrhage into the cyst cavity/2% 11.2% (17.5%, during the total follow-up period) Obscure Obscure Obscure Cho et al. [64 ] Yes/acetic acid (group I) and ethanol (group II) Kidney One/group I: 18 mos., group II: 13 mos. Pain/group I: 48.3%, group II: 12.5 Group I: 90.6% — Group I: 9.4% 0% — Kwon et al. [31 ] Yes/50% acetic acid (group I: sclerosant retention into cyst for 20 min, group II: retention for 5 min) Kidney One/group I: 12 to 52 mos., group II: 7 to 48-mos. Pain/7.7% Group I: 53.1% All the rest, during the total follow-up period Percentage of the reduction rate of the cyst’s volume: 0 0 Nakaoka et al. [49 ] Yes/ethanolamine oleate Liver ( One or two (one patient)/<1 (two patients) up to 95 mos. (median 44.4 mos.) Pain (mild to severe), vasovagal reflex, and mild fever/64.7% — 88.4% (total) — — Yamamoto et al. [32 ] Yes/ethanolamine oleate Liver, kidney One/4 to 10 mos. Fever/28.5% 0 100% 0 0 Yoshida et al. [65 ] Yes/minocycline hydrochloride Liver Session repeated daily for 7-8 days/42 to 153 mos. Pain/22.2% 100% 0% 0% 0%
Jusufovic and Zerem [50 ] Yes/20% NaCl solution Liver One/24 mos. — 40.0% 55% 5% 0 Li et al. [51 ] No (aspiration, only)/bleomycin Kidney One/12 mos. No major 47.0% 36.4% 15.1% 1.5%
