Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression

Figure 2

Distribution of AdipoR2 in OB tissue from intact rats. AdipoR2 immunoreactivity is also found in periglomerular (a), mitral (b), and granular cell layers (c); however, the mark of the immunoreactivity is less intense compared with AdipoR1 (Figure 1). Double immunostaining shows that AdipoR2 colocalize with both neuronal markers (a, b, and c, arrow) and had a strong mark with astrocyte marker (d, arrowhead). Note that mitral cells do not stain with NeuN marker. Nuclei were counterstained with DAPI to identify the different layers of OB. Scale bar corresponds to 20 μm (40x).