Cyanamide Potentiates the Ethanol-Induced Impairment of Receptor-Mediated Endocytosis in a Recombinant Hepatic Cell Line Expressing Alcohol Dehydrogenase Activity

Figure 3

Effects of cyanamide on kinetics of internalization (a) and degradation (b) of ¹²⁵I-ASOR in HAD cell cultures grown in the presence (□) or absence (■□) of 25 mM ethanol. Internalization (a) and degradation (b) of ASOR were determined as described in Figure 3. Data are presented as fmoles ASOR degraded or internalized per million cells and are means ± SEM for 4-5 separate experiments. Values significantly different from controls are indicated, ^∗𝑃<0.05.

(a)

(b)