Review Article

Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context

Figure 6

H-HCA and IHCA. Woman born in 1965. Abnormal liver function tests. Hypertriglyceridemia. Multiple nodules largest 9.5 cm. BMI 21.5. 18-year oral contraceptives. Left hepatectomy in 2011. (a) Fresh specimen—the large reddish nodule is not well limited (black arrows), associated with numerous yellowish small nodules in the surrounding resected parenchyma, sometimes visible under the Glisson’s capsule (white arrows). (b) The small nodules are steatotic. (c) LFABP is lacking in all the small nodules (H-HCA), contrasting with normal expression in the nearby IHCA. (d) CRP is strongly expressed in IHCA, whereas it is negative in the small nodule of H-HCA.
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