Cholinergic Depletion in Alzheimer’s Disease Shown by [¹⁸F]FEOBV Autoradiography

Figure 1

Example of tissues from the prefrontal cortex ((a), (b)) and hippocampus ((c), (d)) from control ((a), (c)), and AD ((b), (d)) tissues showing autoradiography binding (above) and luxol fast blue & cresyl violet staining (below). Studied regions of interest are the cortex, CA1, CA3, and Dentate Gyrus (DG). White matter (WM) was used as baseline.