Cholinergic Depletion in Alzheimer’s Disease Shown by [¹⁸F]FEOBV Autoradiography

Table 1

Subject data for AD patients and controls. There is no significant group difference between controls and AD patients for gender distribution, age, or postmortem delay.

Group	Sex	Age	PMD (h)	Brain wt (g)	ApoE status
AD	M	67	96	1410	3-3
AD	M	92	13.25	1200	3-3
AD	M	66	8.5	1075	4-3
AD	M	67	10.5	1235	3-3
AD	F	77	11.25	855	3-3
AD	M	76	24	1005	4-3
AD	F	74	18	1080	3-3
AD	M	73	26.25	1120	3-3
AD	M	63	21	1200	3-3
AD	F	88	24.5	955	3-3
AD	M	79	19.25	N/A	4-3
AD	M	79	12.75	1135	3-3
AD	M	79	24.75	1210	3-3
Control	M	59	29	1650	3-3
Control	M	60	7.25	1350	3-3
Control	M	65	28.5	1435	3-3
Control	F	74	11	1365	3-3
Control	M	71	76	1250	4-3
Control	M	67	24.75	1300	4-3
Control	M	79	22	1350	3-3
Control	M	70	32.75	1320	3-3
Control	F	90	25.5	1050	3-3
Control	M	91	6.75	1070	3-3
Control	M	68	18.5	1445	4-3
Control	M	80	13	1305	3-3
Control	F	91	26.5	1000	3-3
Control	F	79	17.75	1150	3-3
Control	F	95	23.75	1160	3-3
Control	M	85	26.75	1185	3-3
Control	M	88	8	1150	3-3
Control	F	51	26.25	1336.1	3-3
Control	M	61	8.75	1337.3	3-3
Control	M	59	17.67	1442.5	3-3
AVG; (AD)	77%    Male	75.38	23.85	1123.33	23%    “4-3”
AVG; (Controls)	70%    Male	74.15	22.52	1282.55	15%    “4-3”