The Role of IL-17 in the Association between Pneumococcal Pneumonia and Allergic Sensitization

Table 1

Comparison of IL-17 among the OVA-sensitized/challenged mice and the control mice stratified by pneumococcal pneumonia status.

	OVA-sensitized/challenged mice	Control mice	𝑃 value
Mice with pneumococcal pneumonia	15.94 ± 2.92	22.5 ± 2.44	0.13
Mice without pneumococcal pneumonia	7.43 ± 1.59	17.52 ± 2.12	0.001
𝑃 value	0.01	0.21

Data are presented as mean ± standard error (pg/mL). The lung tissues of mice at the time of death or pneumococcal pneumonia or those of mice without pneumococcal pneumonia at day 7 were homogenized with 2 mL of PBS and frozen at −20°C for subsequent cytokine analysis. IL-17 levels in lung homogenates were determined by ELISA methods.