Inhibited Production of iNOS by Murine J774 Macrophages Occurs via a phoP-Regulated Differential Expression of NFκB and AP-1

<table>Nitrite ion production by J774 cells cultured with different typhoid-causing or non-typhoid-causing Salmonella serovars and co-cultured with IFN-γ. 1: S. typhimurium 14028; 2: S. typhimurium 4/74; 3: S. enteritidis KMS 1977; 4: S. dublin 2229; 5: S. choleraesuis A50; 6: S. kedougou GP; 7: S. montevideo KMS; 8: S. gallinarum; 9: uninfected cells. All experiments were replicated 3 times on at least 5 separate occasions. Statistical bars show significant different (P &lt; 0.05) between nitrite ion production in macrophages infected with typhoidal and nontyphoidal serovars.</table>

Interdisciplinary Perspectives on Infectious Diseases

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Figure 5

Figure 5: Inhibited Production of iNOS by Murine J774 Macrophages Occurs via a phoP-Regulated Differential Expression of NFκB and AP-1